Best practice standards for circular RNA research

AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …

Regulation of microRNA by circular RNA

S Singh, T Sinha, AC Panda - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
Circular (circ) RNAs have emerged as novel regulators of gene expression through various
mechanisms. However, most publications focus on functional circRNAs regulating target …

[HTML][HTML] Regulatory mechanisms of circular RNAs during human mesenchymal stem cell osteogenic differentiation

C Mazziotta, G Badiale, CF Cervellera, M Tognon… - Theranostics, 2024 - ncbi.nlm.nih.gov
Human osteogenic differentiation is a complex and well-orchestrated process which
involves a plethora of molecular players and cellular processes. A growing number of …

[HTML][HTML] CircRNAs: Pivotal modulators of TGF-β signalling in cancer pathogenesis

AA Bhat, G Gupta, R Dahiya, R Thapa, A Gahtori… - Non-coding RNA …, 2024 - Elsevier
The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …

Global identification of mRNA-interacting circular RNAs by CLiPPR-Seq

S Singh, S Shyamal, A Das, AC Panda - Nucleic acids research, 2024 - academic.oup.com
Although the functional role of circular RNA (circRNA) interaction with microRNAs and
proteins has been studied extensively, circRNA interactions with the protein-coding mRNAs …

CircDNAJC11 interacts with TAF15 to promote breast cancer progression via enhancing MAPK6 expression and activating the MAPK signaling pathway

B Wang, H Chen, Y Deng, H Chen, L Xing… - Journal of Translational …, 2023 - Springer
Background Breast cancer (BC) is a common malignant tumor in women worldwide. Circular
RNA (circRNA) has been proven to play a critical role in BC progression. However, the exact …

FUS alters circRNA metabolism in human motor neurons carrying the ALS-linked P525L mutation

A Colantoni, D Capauto, V Alfano, E D'Ambra… - International Journal of …, 2023 - mdpi.com
Deregulation of RNA metabolism has emerged as one of the key events leading to the
degeneration of motor neurons (MNs) in Amyotrophic Lateral Sclerosis (ALS) disease …

The tumorigenic role of circular RNA-MicroRNA Axis in cancer

WR Kim, EG Park, DH Lee, YJ Lee, WH Bae… - International Journal of …, 2023 - mdpi.com
Circular RNAs (circRNAs) are a class of endogenous RNAs that control gene expression at
the transcriptional and post-transcriptional levels. Recent studies have increasingly …

Exploring the multifaceted biologically relevant roles of circRNAs: from regulation, translation to biomarkers

P Hoque, B Romero, RE Akins, M Batish - Cells, 2023 - mdpi.com
CircRNAs are a category of regulatory RNAs that have garnered significant attention in the
field of regulatory RNA research due to their structural stability and tissue-specific …

Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral …

MJ Kamali, M Salehi, M Mostafavi… - Reviews in medical …, 2024 - Wiley Online Library
A significant portion of human cancers are caused by oncoviruses (12%–25%). Oncoviruses
employ various strategies to promote their replication and induce tumourigenesis in host …