Microglia, being the resident immune cells of the central nervous system, play an important
role in maintaining tissue homeostasis and contributes towards brain development under …

The interaction between microglia and astrocytes significantly influences neuroinflammation.
Microglia/astrocytes, part of the neurovascular unit (NVU), are activated by various brain …

Numerous studies demonstrate that neuroinflammation is a key player in the progression of
Alzheimer's disease (AD). Interleukin (IL)-1β is a main inducer of inflammation and therefore …

Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

Alzheimer's disease (AD) is characterized by amyloid beta (Aβ) accumulation, tau pathology
and neuroinflammation. Recently, there has been considerable interest in the role of …

Microglia are the predominant immune cells of the central nervous system (CNS) that exert
key physiological roles required for maintaining CNS homeostasis, notably in response to …

Inflammatory reactions could be both beneficial and detrimental to the brain, depending on
strengths of their activation in various stages of neurodegeneration. Mild activation of …

Anthocyanins are natural phenolic pigments with biological activity. They are well-known to
have potent antioxidant and antiinflammatory activity, which explains the various biological …

The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional,
motivational, and social reward associations together with their more demanding cognitive …

Inflammation is associated with many neurodegenerative diseases, including Alzheimer's
disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. In this …