[HTML][HTML] Sensitization in transplantation: assessment of risk (STAR) 2019 working group meeting report

AR Tambur, P Campbell, AS Chong, S Feng… - American Journal of …, 2020 - Elsevier
The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR
report to further clarify the expectations, limitations, perceptions, and utility of alloimmune …

[HTML][HTML] Artificial intelligence: present and future potential for solid organ transplantation

A Peloso, B Moeckli, V Delaune… - Transplant …, 2022 - frontierspartnerships.org
Artificial intelligence (AI) refers to computer algorithms used to complete tasks that usually
require human intelligence. Typical examples include complex decision-making and-image …

Biological characteristics and predictive model of biopsy-proven acute rejection (BPAR) after kidney transplantation: evidences of multi-omics analysis

Q Han, X Zhang, X Ren, Z Hang, Y Yin, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Objectives: Early diagnosis and detection of acute rejection following kidney transplantation
are of great significance for guiding the treatment and improving the prognosis of renal …

Pathophysiology of rejection in kidney transplantation

CL Tamargo, S Kant - Journal of Clinical Medicine, 2023 - mdpi.com
Kidney transplantation has been the optimal treatment for end-stage kidney disease for
almost 70 years, with increasing frequency over this period. Despite the prevalence of the …

[HTML][HTML] Omics-based biomarkers for diagnosis and prediction of kidney allograft rejection

JH Lim, BH Chung, SH Lee, HY Jung… - The Korean Journal …, 2022 - ncbi.nlm.nih.gov
Kidney transplantation is the preferred treatment for patients with end-stage kidney disease,
because it prolongs survival and improves quality of life. Allograft biopsy is the gold standard …

Surfing the big data wave: omics data challenges in transplantation

R Ba, E Geffard, V Douillard, F Simon, L Mesnard… - …, 2022 - journals.lww.com
In both research and care, patients, caregivers, and researchers are facing a leap forward in
the quantity of data that are available for analysis and interpretation, marking the daunting …

Pathway-level multi-omics analysis of the molecular mechanisms underlying the toxicity of long-term tacrolimus exposure

NTH Yen, NK Phat, JH Oh, SM Park, KS Moon… - Toxicology and Applied …, 2023 - Elsevier
Tacrolimus (TAC)-based treatment is associated with nephrotoxicity and hepatotoxicity;
however, the underlying molecular mechanisms responsible for this toxicity have not been …

Molecular markers of kidney transplantation outcome: current omics tools and future developments

M Lepoittevin, T Kerforne, L Pellerin, T Hauet… - International Journal of …, 2022 - mdpi.com
Purpose of review: The emerging field of molecular predictive medicine is aiming to change
the traditional medical approach in renal transplantation. Many studies have explored …

Molecular diversity of clinically stable human kidney allografts

D Rychkov, S Sur, M Sirota, MM Sarwal - JAMA Network Open, 2021 - jamanetwork.com
Importance Clinical decision and immunosuppression dosing in kidney transplantation rely
on transplant biopsy tissue histology even though histology has low specificity, sensitivity …

Noninvasive biomarkers in monitoring kidney allograft health

JM O'Callaghan, SR Knight - Current Opinion in Organ …, 2019 - journals.lww.com
Noninvasive, rapid, and accurate tests for risk-prediction and diagnosis in renal transplant
allografts are urgently required. The ideal candidate is one that can be measured in either …