Ferroptosis and cuproptosis, regulated forms of cell death resulting from metal ion
accumulation, are closely related in terms of occurrence, cell metabolism, signaling …

As the vanguard against implant-associated infections (IAIs), macrophages facilitate the
phagocytosis and pro-inflammatory polarization of planktonic and biofilm infections, but …

The mycotoxin ochratoxin A (OTA) causes nephrotoxicity, hepatotoxicity, and immunotoxicity
in animals and humans. The farnesoid X receptor (FXR) is a member of the NR family and is …

Ferroptosis is an oxidative form of iron-dependent cell death characterized by the
accumulation of lipid peroxides on membranes. Iron and lipids containing polyunsaturated …

Ferroptosis is a form of iron-related oxidative cell death governed by an integrated redox
system, encompassing pro-oxidative proteins and antioxidative proteins. These proteins …

Ferroptosis, spurred by excess labile iron and lipid peroxidation, is implicated in various
diseases. Advances have been made in comprehending the lipid-peroxidation side of …

There are few effective and safe neuroprotective agents for the treatment of ischemic stroke
currently. Caffeic acid is a phenolic acid that widely exists in a number of plant species …

Copper is an essential trace element, and plays a vital role in numerous physiological
processes within the human body. During normal metabolism, the human body maintains …

Ferroptosis has attracted significant attention as a new mechanism of cell death. Sorafenib
(SRF) is widely considered a prototypical ferroptosis-inducing drug, particularly for liver …

Ferroptosis is a type of regulated cell death characterized by iron accumulation and
uncontrolled lipid peroxidation, leading to plasma membrane rupture and intracellular …