Copper (Cu) is one of the most significant trace elements in the body, but it is also a
widespread environmental toxicant health. Ferroptosis is a newly identified programmed cell …

As a devastating disease, breast cancer has been responsible for decrease in life
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …

Cancer cells often exhibit defects in the execution of cell death, resulting in poor clinical
outcomes for patients with many cancer types. Ferroptosis is a newly discovered form of …

Regulation of the oxidative stress response is crucial for the management and prognosis of
traumatic brain injury (TBI). The copper chaperone Antioxidant 1 (Atox1) plays a crucial role …

Melanoma, the most aggressive form of human skin cancer, has been under investigation to
reach the most efficient treatment. Surgical resection for early-diagnosed primary melanoma …

As a new type of pollutant, microplastics (MPs) commonly exist in today's ecosystems,
causing damage to the ecological environment and the health of biological organisms …

Chronic kidney disease (CKD) has become a global public health problem with high
morbidity and mortality. Renal fibrosis can lead to end-stage renal disease (ESRD) …

Cuproptosis is dependent on mitochondrial respiration modulation by targeting lipoylated
tricarboxylic acid cycle (TCA) cycle proteins, showing great potential in cancer treatment …

Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer,
characterized by invasiveness, local lymph node metastasis, and poor prognosis. Traditional …

Ferroptosis has received increasing attention as a novel nonapoptotic programmed death.
Recently, iron-based nanomaterials have been extensively exploited for efficient tumor …