Background Cholangiocarcinoma represents a malignant neoplasm originating from the
hepatobiliary tree, with a subset of tumors developing inside the liver. Intrahepatic …

Background RPLP2, an integral part of ribosomal stalk, plays an important role in the
tumorigenesis of various cancers. However, its specific effect on HCC remains elusive …

Abstract Ethnopharmacological relevance Hua Zhuo Ning Fu Decoction (HZD) is an
empirical prescription from traditional Chinese medicine that shows excellent clinical results …

Certain strains of probiotic bacteria can secret functional substances namely digestive
enzymes and functional peptides to regulate physiological conditions such as digestion and …

Mitochondria are the centers of energy and material metabolism, and they also serve as the
storage and dispatch hubs of metal ions. Damage to mitochondrial structure and function …

Cognitive dysfunction occurs mainly in certain diseases and in the pathological process of
aging. In addition to this, it is also widespread in patients undergoing anesthesia, surgery …

Copper (Cu) is a common trace element additive in animal and human foods, and excessive
intake of Cu has been shown to cause hepatotoxicity, but the underlying mechanism …

Ferroptosis is an emerging non‐apoptotic death process, mainly involving lipid peroxidation
(LPO) caused by iron accumulation, which is potentially lethal to the intrinsically apoptotic …

Ferroptosis was first reported as a separate modality of regulated cell death in 2008 and
distinguished under its current name in 2012 after it was first induced with erastin. In the …

Sepsis, a life-threatening condition resulting from a dysregulated response to pathogen
infection, poses a significant challenge in clinical management. Here, we report a novel role …