Abstract The interleukin-1 (IL-1) family of cytokines and receptors are implicated in the
functioning of innate and adaptive immunity and the genesis of inflammation. They are …

Prior studies have found associations between atopic dermatitis (AD) and comorbidities
including depression, obesity, asthma, and allergic rhinitis. While observational studies often …

Interleukin (IL)-18, an interferon-γ inducer, belongs to the IL-1 family of pleiotropic pro-
inflammatory factors, and IL-18 binding protein (IL-18BP) is a native antagonist of IL-18 in …

Mouse models for atopic dermatitis (AD) are an indispensable preclinical research tool for
testing new candidate AD therapeutics and for interrogating AD pathobiology in vivo. In this …

Atopic dermatitis (AD) is maintained by a variety of cells and inflammatory mediators,
including eosinophils and histamine. We recently reported that eosinophils from AD patients …

The predominant function of the skin is to serve as a barrier—to protect against external
insults and to prevent water loss. Junctional and structural proteins in the stratum corneum …

Inflammatory diseases of the skin, including atopic dermatitis and psoriasis, have gained
increasing attention with rising incidences in developed countries over the past decades …

Dengue fever is an infection by the dengue virus (DENV) transmitted by vector mosquitoes. It
causes many infections in tropical and subtropical countries every year, thus posing a …

Ethnopharmacological relevance Atopic dermatitis (AD) is a persistent, recurrent
inflammatory skin disorder with a rapid upward trend worldwide. The first-line treatment for …

Atopic dermatitis (AD) is a common, chronic, and recurring inflammatory skin disease.
Physalis alkekengi L. var. franchetii (Mast) Makino (PAF), a traditional Chinese medicine, is …