Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction
High levels of lactate are positively associated with the prognosis and mortality in patients
with heart attack. Endothelial-to-mesenchymal transition (EndoMT) plays an important role in …
with heart attack. Endothelial-to-mesenchymal transition (EndoMT) plays an important role in …
Mechanisms regulating wound healing: Functional changes in biology mediated by lactate and histone lactylation
H Wu, W Liang, M Han, Y Zhen, L Chen… - Journal of Cellular …, 2023 - Wiley Online Library
The high incidence, low healing rate and huge economic burden of wounds (especially
chronic wounds) worldwide remain a great challenge for clinical staff and patients. The …
chronic wounds) worldwide remain a great challenge for clinical staff and patients. The …
Changes in plasma endocan level are related to circulatory but not respiratory failure in critically ill patients with COVID-19
M Lipińska-Gediga, A Lemańska-Perek, W Gozdzik… - Scientific Reports, 2023 - nature.com
The aim of this prospective, observational study was to assess whether changes in the level
of endocan, a marker of endothelial damage, may be an indicator of clinical deterioration …
of endocan, a marker of endothelial damage, may be an indicator of clinical deterioration …
Metabolite profiles of diabetes mellitus and response to intervention in anti-hyperglycemic drugs
Y Liu, D Wang, YP Liu - Frontiers in Endocrinology, 2023 - frontiersin.org
Type 2 diabetes mellitus (T2DM) has become a major health problem, threatening the
quality of life of nearly 500 million patients worldwide. As a typical multifactorial metabolic …
quality of life of nearly 500 million patients worldwide. As a typical multifactorial metabolic …
Predictions based on inflammatory cytokine profiling of Egyptian COVID-19 with 2 potential therapeutic effects of certain marine-derived compounds
Backgrounds A worldwide coronavirus pandemic has affected many healthcare systems in
2019 (COVID-19). Following viral activation, cytokines and chemokines are released …
2019 (COVID-19). Following viral activation, cytokines and chemokines are released …
Association between lactate metabolism‑related molecules and venous thromboembolism: A study based on bioinformatics and an in vitro model
Z Qin, J Chen, J Zhang, H Lu… - Experimental and …, 2024 - spandidos-publications.com
Venous thromboembolism (VTE) is characterized by a high recurrence rate and adverse
consequences, including high mortality. Damage to vascular endothelial cells (VECs) serves …
consequences, including high mortality. Damage to vascular endothelial cells (VECs) serves …
The association between lactate dehydrogenase to serum albumin ratio and in-hospital mortality in patients with pulmonary embolism: a retrospective analysis of the …
J Hu, Y Zhou - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Background Lactate dehydrogenase (LDH) and albumin (ALB) were found to be significantly
correlated with mortality in pulmonary embolism (PE) patients. However, data regarding the …
correlated with mortality in pulmonary embolism (PE) patients. However, data regarding the …
Entwöhnung von der Langzeitbeatmung nach ARDS auf einer spezialisierten Weaning-Einheit–ein retrospektiver Vergleich von Patienten mit und ohne SARS-CoV-2 …
T Müller, P Lennemann, J Mannschreck, A Daher… - …, 2023 - thieme-connect.com
Fragestellung Bislang sind nur wenige Daten über den Verlauf von Patienten mit COVID-19
im prolongierten Weaning vorhanden. Die aktuelle Arbeit vergleicht deshalb Patienten mit …
im prolongierten Weaning vorhanden. Die aktuelle Arbeit vergleicht deshalb Patienten mit …