Recent review of COVID-19 management: Diagnosis, treatment and vaccination

VP Chavda, S Vuppu, T Mishra, S Kamaraj… - Pharmacological …, 2022 - Springer
The idiopathic Coronavirus disease 2019 (COVID-19) pandemic outbreak caused by the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached global …

mRNA-based vaccines and therapeutics for COVID-19 and future pandemics

VP Chavda, S Soni, LK Vora, S Soni, A Khadela… - Vaccines, 2022 - mdpi.com
An unheard mobilization of resources to find SARS-CoV-2 vaccines and therapies has been
sparked by the COVID-19 pandemic. Two years ago, COVID-19's launch propelled mRNA …

Fast-track development of vaccines for SARS-CoV-2: the shots that saved the world

VP Chavda, Q Yao, LK Vora, V Apostolopoulos… - Frontiers in …, 2022 - frontiersin.org
In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …

Molnupiravir: A versatile prodrug against SARS-CoV-2 variants

D Teli, P Balar, K Patel, A Sharma, V Chavda, L Vora - Metabolites, 2023 - mdpi.com
The nucleoside analog β-DN 4-hydroxycytidine is the active metabolite of the prodrug
molnupiravir and is accepted as an efficient drug against COVID-19. Molnupiravir targets the …

Potential anti-SARS-CoV-2 prodrugs activated by phosphorylation and their role in the aged population

VP Chavda, D Teli, PC Balar, D Vaghela, HK Solanki… - Molecules, 2023 - mdpi.com
The COVID-19 pandemic has flared across every part of the globe and affected populations
from different age groups differently. People aged from 40 to 80 years or older are at an …

Dendritic cell-based vaccine: The state-of-the-art vaccine platform for COVID-19 management

VP Chavda, AB Patel, LK Vora… - Expert review of …, 2022 - Taylor & Francis
Introduction A correlation between new coronaviruses and host immunity, as well as the role
of defective immune function in host response, would be extremely helpful in understanding …

[HTML][HTML] The potential role of ferroptosis in COVID-19-related cardiovascular injury

L Yang, Y Wu, W Jin, N Mo, G Ye, Z Su, L Tang… - Biomedicine & …, 2023 - Elsevier
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
emerged as a global health threat in 2019. An important feature of the disease is that …

L‐Proline Derived Thioamide Small Organic Molecule for the α‐Stereoselective Synthesis of 2‐Deoxyglycosides

A Tiwari, A Khanam, A Kumar, M Lal… - Advanced Synthesis …, 2023 - Wiley Online Library
L‐Prolinethioamide catalyzes direct stereoselective glycosylation of glycal donors to access
2‐deoxyglycosides under moderate reaction conditions. This proposed glycosylation …

Co-infection associated with SARS-CoV-2 and their management

VP Chavda, AB Patel, A Pandya, LK Vora… - Future science …, 2022 - Taylor & Francis
SARS-CoV-2 was discovered in Wuhan, China and quickly spread throughout the world.
This deadly virus moved from person to person, resulting in severe pneumonia, fever, chills …

[HTML][HTML] Metabolic modeling of single bronchoalveolar macrophages reveals regulators of hyperinflammation in COVID-19

Q Zhao, Z Yu, S Zhang, XR Shen, H Yang, Y Xu, Y Liu… - Iscience, 2022 - cell.com
SARS-CoV-2 infection induces imbalanced immune response such as hyperinflammation in
patients with severe COVID-19. Here, we studied the immunometabolic regulatory …