Brain‐derived extracellular vesicles: Potential diagnostic biomarkers for central nervous system diseases

X Xu, Z Iqbal, L Xu, C Wen, L Duan… - Psychiatry and …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are membrane‐enclosed nanovesicles secreted by cells into the
extracellular space and contain functional biomolecules, eg signaling receptors, bioactive …

[HTML][HTML] Circular RNAs in glioma: Molecular functions and pathological implications

C Tang, X He, L Jia, X Zhang - Non-coding RNA research, 2023 - Elsevier
Circular RNAs (circRNAs) are a special class of non-coding RNAs with the ring structure.
They are stable, abundant and conservative across mammals. The biogenesis and …

[HTML][HTML] Physiological and pathological functions of circular RNAs in the nervous system

M Zhou, S Li, C Huang - Neural Regeneration Research, 2024 - journals.lww.com
Circular RNAs (circRNAs) are a class of covalently closed single-stranded RNAs that are
expressed during the development of specific cells and tissues. CircRNAs play crucial roles …

Exosomes derived from mesenchymal stem cells: novel effects in the treatment of ischemic stroke

Y Xiong, J Song, X Huang, Z Pan… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke is defined as an infarction in the brain, caused by impaired cerebral blood
supply, leading to local brain tissue ischemia, hypoxic necrosis, and corresponding …

Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis

X Yi, J Chen, D Huang, S Feng, T Yang, Z Li… - Frontiers in …, 2022 - frontiersin.org
Exosomes are a heterogeneous subset of extracellular vesicles (EVs) that biogenesis from
endosomes. Besides, exosomes contain a variety of molecular cargoes including proteins …

Exosomes: potential targets for the diagnosis and treatment of neuropsychiatric disorders

H Li, Y Yuan, Q Xie, Z Dong - Journal of Translational Medicine, 2024 - Springer
The field of neuropsychiatry is considered a middle ground between neurological and
psychiatric disorders, thereby bridging the conventional boundaries between matter and …

Circular RNAs in ischemic stroke: biological role and experimental models

C Siracusa, J Sabatino, I Leo, C Eyileten, M Postuła… - Biomolecules, 2023 - mdpi.com
Ischemic stroke is among the leading causes of morbidity, disability, and mortality
worldwide. Despite the recent progress in the management of acute ischemic stroke, timely …

Excited-state intramolecular proton transfer (ESIPT)-based fluorescent probes for biomarker detection: design, mechanism, and application

H Gu, W Wang, W Wu, M Wang, Y Liu, Y Jiao… - Chemical …, 2023 - pubs.rsc.org
Biomarkers are essential in biology, physiology, and pharmacology; thus, their detection is
of extensive importance. Fluorescent probes provide effective tools for detecting biomarkers …

The autophagy in ischemic stroke: A regulatory role of non-coding-RNAs

S Xiaoqing, C Yinghua, Y Xingxing - Cellular signalling, 2023 - Elsevier
Ischemic stroke (IS) is a central nervous system neurological disorder ascribed to an acute
focal trauma, with high mortality and disability, leading to a heavy burden on family and …

Circular RNAs: Promising Treatment Targets and Biomarkers of Ischemic Stroke

G Xu, G Liu, Z Wang, Y Li, W Fang - International journal of molecular …, 2023 - mdpi.com
Ischemic stroke is one of the most significant causes of morbidity and mortality worldwide.
However, there is a dearth of effective drugs and treatment methods for ischemic stroke …