Potential resistance of SARS-CoV-2 main protease (Mpro) against protease inhibitors: lessons learned from HIV-1 protease
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …
[HTML][HTML] Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infections
S Najafi, SC Tan, S Aghamiri, P Raee… - Biomedicine & …, 2022 - Elsevier
Viral infections are a common cause of morbidity worldwide. The emergence of Coronavirus
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …
Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel …
[HTML][HTML] Utilization of immunological ratios in HIV: Implications for monitoring and therapeutic strategies
Human immunodeficiency virus (HIV) infection remains a significant global health concern,
necessitating ongoing research and innovation in the quest for improved disease …
necessitating ongoing research and innovation in the quest for improved disease …
Primary care guidance for persons with human immunodeficiency virus: 2020 update by the HIV Medicine Association of the Infectious Diseases Society of America
MA Thompson, MA Horberg, AL Agwu… - Clinical infectious …, 2021 - academic.oup.com
Advances in antiretroviral therapy (ART) have made it possible for persons with human
immunodeficiency virus (HIV) to live a near expected life span, without progressing to AIDS …
immunodeficiency virus (HIV) to live a near expected life span, without progressing to AIDS …
Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2020 recommendations of the International Antiviral Society–USA Panel
MS Saag, RT Gandhi, JF Hoy, RJ Landovitz… - Jama, 2020 - jamanetwork.com
Importance Data on the use of antiretroviral drugs, including new drugs and formulations, for
the treatment and prevention of HIV infection continue to guide optimal practices. Objective …
the treatment and prevention of HIV infection continue to guide optimal practices. Objective …
A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CLpro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19
M de Vries, AS Mohamed, RA Prescott… - Journal of …, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
coronavirus disease 2019 (COVID-19). There is a dire need for novel effective antivirals to …
coronavirus disease 2019 (COVID-19). There is a dire need for novel effective antivirals to …
[HTML][HTML] 2019 update of the drug resistance mutations in HIV-1
AM Wensing, V Calvez… - Topics in antiviral …, 2019 - ncbi.nlm.nih.gov
The 2019 edition of the IAS-USA drug resistance mutations list updates the Figure last
published in January 2017. The mutations listed are those that have been identified by …
published in January 2017. The mutations listed are those that have been identified by …
[HTML][HTML] Highly active antiretroviral therapy (HAART)
JS Eggleton, S Nagalli - 2020 - europepmc.org
Objectives: Describe the treatment considerations for patients with HIV. Identify the most
common adverse events associated with highly active antiretroviral therapy (HAART) …
common adverse events associated with highly active antiretroviral therapy (HAART) …
Transmitted drug resistance among human immunodeficiency virus (HIV)-1 diagnoses in the United States, 2014–2018
RP McClung, AM Oster, MCB Ocfemia… - Clinical Infectious …, 2022 - academic.oup.com
Background Transmitted human immunodeficiency virus (HIV) drug resistance can threaten
the efficacy of antiretroviral therapy and pre-exposure prophylaxis (PrEP). Drug-resistance …
the efficacy of antiretroviral therapy and pre-exposure prophylaxis (PrEP). Drug-resistance …
Drug resistance mutations in HIV: new bioinformatics approaches and challenges
Highlights•Machine learning is increasingly used to predict and understand drug resistance
in HIV.•Phylogenetics helps to track the emergence and spread of HIV drug resistance …
in HIV.•Phylogenetics helps to track the emergence and spread of HIV drug resistance …