Widely used in global households, fenugreek is well known for its culinary and medicinal
uses. The various reported medicinal properties of fenugreek are by virtue of the different …

The recent emergence of the severe acute respiratory disease caused by a novel
coronavirus remains a concern posing many challenges to public health and the global …

It is believed that the ethanol extract of mangosteen rind (EEMR) with the marker
compounds alpha-mangostin, gamma-mangostin, and xanthone can be used for diabetes …

In earlier work, we used partially overlapped synthetic peptides as a tool to find regions of
interaction between the human FSH hormone and its receptor, aiming to find possible …

Prediction of protein-ligand (PL) binding affinity remains the key to drug discovery. Popular
approaches in recent years involve graph neural networks (GNNs), which are used to learn …

Significantly more 'outliers' can be produced from a non-Gaussian distribution than one
would anticipate were the statistics to conform to a normal distribution. Using ensemble …

Optimization of binding affinities for ligands to their target protein is a primary objective in
rational drug discovery. Herein we report on a collaborative study that evaluates various …

Selectively inhibiting the FXa has a broad therapeutic window as an anticoagulant target
because of its starting position of the common pathway of the coagulation cascade which …

Hyperpigmentation is a skin-related problem caused by overproduction of melanin due to
tyrosinase overexpression. Several compounds from Nigella sativa (N. sativa) have showed …

The COVID-19 outbreak is caused by the Severe Acute Respiratory Syndrome Coronavirus
2 (SARS-CoV-2). Various in-silico studies have been conducted to find alternative drugs …