We report the first administration of an orally active aldosterone synthase inhibitor, LCI699,
to 14 patients with primary aldosteronism. After a 2-week placebo run-in, patients received …

Objective: To develop a prediction model for clinical outcomes after unilateral
adrenalectomy for unilateral primary aldosteronism. Summary Background Data: Unilateral …

Context Failure of plasma aldosterone suppression during fludrocortisone suppression
testing (FST) or saline suppression testing (SST) confirms primary aldosteronism (PA) …

Primary aldosteronism (PA) secondary to excessive and/or autonomous aldosterone
secretion from the renin–angiotensin system accounts for∼ 10% of cases of hypertension …

Introduction: Adrenal incidentalomas are detected in approximately 4% of patients
undergoing high-resolution abdominal imaging studies. The majority of adrenal …

Primary aldosteronism used to be considered a rare cause of secondary hypertension.
However, accruing evidence indicates that primary aldosteronism is more common than …

Background Primary aldosteronism (PA) is a common but under‐recognized cause of
secondary hypertension. Data directly comparing screening rates across single and …

Resistant hypertension is common in the chronic kidney disease population and conveys
increased risk for adverse cardiovascular outcomes and the development of kidney failure …

Background: Despite hyperaldosteronism being suggested as predisposing to arrhythmias,
the relationship between atrial fibrillation and primary aldosteronism remains uncertain …

Background Kidney impairment is noted in primary aldosteronism (PA), and probably
initiated by glomerular hyperfiltration. Methods A prospectively defined survey was …