Context: In primary aldosteronism (PA), glomerular hyperfiltration due to excessive
aldosterone is considered to underestimate actual renal damage. Objective: Our objectives …

Context: Adrenal venous sampling (AVS) is used to distinguish bilateral from unilateral
primary aldosteronism (PA). Due to its limited availability, clinical prediction scores have …

The type 1 parathyroid hormone receptor (PTHR1) binds, with equal affinity, two ligands with
distinct biological functions: PTH, the major peptide hormone controlling calcium …

Primary aldosteronism is much more common than previously thought. The high prevalence
of primary aldosteronism, the damage this condition does to the heart, blood vessels and …

The role of aldosterone in the pathogenesis of hypertension and cardiovascular diseases
has been clearly shown in congestive heart failure and endocrine hypertension due to …

Context: Primary aldosteronism (PA) is an established cause of hypertension, whereas high-
normal serum aldosterone levels have been linked to an increased risk for hypertension …

Aldosterone and cortisol, the main mineralocorticoid and glucocorticoid hormones in
humans, are produced in the adrenal cortex, which is composed of three concentric zones …

An association between primary aldosteronism and metabolism disorders has been
reported. The aim of this retrospective study was to test for this association by comparison …

Slowing the progression of chronic kidney diseases (CKDs) requires new and effective
treatment approaches. Aldosterone classically acts on the distal nephron: it facilitates …

Availability and wider application of the plasma aldosterone/renin ratio (ARR) as a
screening test for primary aldosteronism (PA) has led to the recognition that PA is the most …