Small molecule inhibitors targeting m6A regulators
G Feng, Y Wu, Y Hu, W Shuai, X Yang, Y Li… - Journal of Hematology & …, 2024 - Springer
As the most common form of epigenetic regulation by RNA, N6 methyladenosine (m6A)
modification is closely involved in physiological processes, such as growth and …
modification is closely involved in physiological processes, such as growth and …
Recent advances in the reciprocal regulation of m6A modification with non-coding RNAs and its therapeutic application in acute myeloid leukemia
J Yang, F Liang, F Zhang, H Zhao, Q Gong… - Pharmacology & …, 2024 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is one of the most common modifications of RNA in
eukaryotic cells and is involved in mRNA metabolism, including stability, translation …
eukaryotic cells and is involved in mRNA metabolism, including stability, translation …
New evidence for a role of DANCR in cancers: a comprehensive review
R Yuan, Z Xu, S Zhang, X Cao, A Dai… - Journal of Translational …, 2024 - Springer
Cancer remains a leading cause of mortality and poses a substantial threat to public health.
Studies have revealed that Long noncoding RNA DANCR is a cytoplasmic lncRNA whose …
Studies have revealed that Long noncoding RNA DANCR is a cytoplasmic lncRNA whose …
Differential lncRNA profiles of blood plasma-derived exosomes from systemic lupus erythematosus
X Peng, L Ma, J Miao, S Xu, Z Shuai - Gene, 2024 - Elsevier
Abstract Introduction Long non-coding RNAs (lncRNAs) dysregulation is key in the
pathogenesis of systemic lupus erythematosus (SLE), but the role of exosomal lncRNAs in …
pathogenesis of systemic lupus erythematosus (SLE), but the role of exosomal lncRNAs in …
[HTML][HTML] LncRNA SH3BP5-AS1 promotes hepatocellular carcinoma progression by sponging miR-6838-5p and activation of PTPN4
X Zhao, X Zhu, C Xiao, Z Hu - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: Long noncoding RNAs (LncRNAs) have been demonstrated to have significant
roles in the carcinogenesis of hepatocellular carcinoma (HCC). In this work, we sought to …
roles in the carcinogenesis of hepatocellular carcinoma (HCC). In this work, we sought to …
Dynamic alterations of the transcriptome-wide m6A methylome in cytogenetically normal acute myeloid leukaemia during initial diagnosis and relapse
J Zhang, T Liu, Y Wang, X Yan, Y Li, F Xu, R Zhang - Genomics, 2023 - Elsevier
Accumulating studies have indicated that N6-methyladenosine (m 6 A) plays an important
role in acute myeloid leukaemia (AML). However, little is known about the m 6 A methylome …
role in acute myeloid leukaemia (AML). However, little is known about the m 6 A methylome …
IGF2BP1 facilitates non-small cell lung cancer progression by regulating the KIF2A-mediated Wnt/β-catenin pathway
M Sun, L Wang, L Ge, D Xu, R Zhang - Functional & Integrative Genomics, 2024 - Springer
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) are crucially implicated in the
cancer progression. The current study intends to excavate and clarify the mechanisms of the …
cancer progression. The current study intends to excavate and clarify the mechanisms of the …