Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

[HTML][HTML] Hydrogen sulfide: An endogenous regulator of the immune system

N Dilek, A Papapetropoulos, T Toliver-Kinsky… - Pharmacological …, 2020 - Elsevier
Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Allicin and health: A comprehensive review

B Salehi, P Zucca, IE Orhan, E Azzini… - Trends in Food Science …, 2019 - Elsevier
Background Allicin is an organosulfur and defensive compound found in garlic (Allium
sativum L.) and other Allium species. Its unique odor is easily detectable, and its effects on …

[HTML][HTML] Implications of hydrogen sulfide in colorectal cancer: Mechanistic insights and diagnostic and therapeutic strategies

H Lin, Y Yu, L Zhu, N Lai, L Zhang, Y Guo, X Lin… - Redox biology, 2023 - Elsevier
Hydrogen sulfide (H 2 S) is an important signaling molecule in colorectal cancer (CRC). It is
produced in the colon by the catalytic synthesis of the colonocytes' enzymatic systems and …

Vascular biology of hydrogen sulfide

NL Kanagy, C Szabo… - American Journal of …, 2017 - journals.physiology.org
Hydrogen sulfide (H2S) is a ubiquitous signaling molecule with important functions in many
mammalian organs and systems. Observations in the 1990s ascribed physiological actions …

[HTML][HTML] Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Striking luminescence phenomena of carbon dots and their applications as a double ratiometric fluorescence probes for H2S detection

Y Xu, H Yu, L Chudal, NK Pandey, EH Amador… - Materials Today …, 2021 - Elsevier
Here, we report some new observations on the luminescence of carbon dots (CDs) that are
passivated with polyethylene glycol, and explored them, for the first time, as highly sensitive …

A new hope for a devastating disease: hydrogen sulfide in Parkinson's disease

X Cao, L Cao, L Ding, J Bian - Molecular Neurobiology, 2018 - Springer
Hydrogen sulfide (H 2 S) has been regarded as the third gaseous transmitter alongside nitric
oxide (NO) and carbon monoxide (CO). In mammalian brain, H 2 S is produced redundantly …