Recent advances in nitrogen-containing heterocyclic compounds as receptor tyrosine kinase inhibitors for the treatment of cancer: biological activity and structural …
Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …
Immobilization of pectinase on chitosan-alginate-clay composite beads: Experimental, DFT and molecular docking studies
A Aksu, S Çetinkaya, AF Yenidünya, ŞA Çetinus… - Journal of Molecular …, 2023 - Elsevier
Pectinase was immobilized on chitosan-alginate-clay (CAC) beads using epichlorohydrin
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …
(ECH) as the crosslinker. Prepared beads and immobilization product were analyzed by …
Synthesis of new carboxylates and sulfonates containing thiazolidin-4-one ring and evaluation of inhibitory properties against some metabolic enzymes
A series of thizaolidin-4-one derivatives (3a-o) was synthesized with excellent yield (94–
97%) and the structures of the compounds were characterized with Fourier-transform …
97%) and the structures of the compounds were characterized with Fourier-transform …
Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies
In the present work, a series of compounds containing imidazole and hydrazone structural
frameworks were synthesized and characterized using various spectral techniques …
frameworks were synthesized and characterized using various spectral techniques …
Vanadium (IV) complexes of salicylaldehyde-based furoic acid hydrazones: Synthesis, BSA binding and in vivo antidiabetic potential
Solution synthesis afforded five novel neutral heteroleptic octahedral paramagnetic
mononuclear oxidovanadium (IV) complexes of general composition [VO (bpy) L], where L is …
mononuclear oxidovanadium (IV) complexes of general composition [VO (bpy) L], where L is …
Antioxidant enzyme activities, molecular docking studies, MM-GBSA, and molecular dynamic of chlorpyrifos in freshwater fish Capoeta umbla
Chlorpyrifos (CPF), which was started to be used in 1965, is a broad spectrum
organophosphate insecticide that is used more and more day by day. Commonly used to …
organophosphate insecticide that is used more and more day by day. Commonly used to …
Corrosion inhibition of Carbon Steel using a new morpholine-based ligand during acid pickling: Experimental and theoretical studies
Here, a novel, relatively inexpensive Schiff base ligand (HL) has been studied as a
corrosion inhibitor for the protection of steel in acidic solution. Different concentrations (0–25 …
corrosion inhibitor for the protection of steel in acidic solution. Different concentrations (0–25 …
[HTML][HTML] In vitro and in silico evaluation of the antimicrobial and antioxidant activities of spiropyrazoline oxindole congeners
M Chalkha, K Chebbac, H Nour, A Nakkabi… - Arabian Journal of …, 2024 - Elsevier
The search for novel powerful antimicrobial and antioxidant agents is considered a dynamic
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
Novel 1, 2, 3, 4-tetrahydroisoquinoline-based Schiff bases as laccase inhibitors: Synthesis and biological activity, 3D-QSAR, and molecular docking studies
H Xu, X Lu, T Sun, Q He, Y Qi, Y Lin, X Yang… - Journal of Molecular …, 2023 - Elsevier
Laccase is considered a potential target in the field of agricultural fungicides. To promote the
discovery and development of compounds with laccase inhibitory activity, herein, taking …
discovery and development of compounds with laccase inhibitory activity, herein, taking …
Design, synthesis, In-vitro, In-silico and DFT studies of novel functionalized isoxazoles as antibacterial and antioxidant agents
A Arzine, O Abchir, M Chalkha, K Chebbac… - … Biology and Chemistry, 2024 - Elsevier
A series of new isoxazolederivatives incorporating the sulfonate ester function has been
synthesized from 2-benzylidenebenzofuran-3 (2 H)-one, known as aurone. The synthesis of …
synthesized from 2-benzylidenebenzofuran-3 (2 H)-one, known as aurone. The synthesis of …