The human endogenous retrovirus link between genes and environment in multiple sclerosis and in multifactorial diseases associating neuroinflammation
H Perron, A Lang - Clinical reviews in allergy & immunology, 2010 - Springer
Endogenous retroviruses represent about 8% of the human genome and belong to the
superfamily of transposable and retrotransposable genetic elements. Altogether, these …
superfamily of transposable and retrotransposable genetic elements. Altogether, these …
Clinical implications of interferon‐γ genetic and epigenetic variants
NLD Smith, DW Denning - Immunology, 2014 - Wiley Online Library
Summary Interferon‐γ (IFN‐γ) is an integral and critical molecule of the immune system, with
multiple functions, mostly related to the T helper type 1 (Th1) response to infection. It is …
multiple functions, mostly related to the T helper type 1 (Th1) response to infection. It is …
Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma
CL Hsu, KW Lui, LM Chi, YC Kuo, YK Chao… - Journal of Experimental …, 2018 - Springer
Background Patient-derived xenograft (PDX) tumor model has become a new approach in
identifying druggable tumor mutations, screening and evaluating personalized cancer drugs …
identifying druggable tumor mutations, screening and evaluating personalized cancer drugs …
[HTML][HTML] Whole genome microarray analysis of gene expression in subjects with fragile X syndrome
DC Bittel, N Kibiryeva, MG Butler - Genetics in Medicine, 2007 - Elsevier
Purpose Fragile X syndrome, the most common inherited form of human mental retardation,
arises as a consequence of a large expansion of a CGG trinucleotide repeat in 5 …
arises as a consequence of a large expansion of a CGG trinucleotide repeat in 5 …
Preparation and validation of the first WHO international genetic reference panel for Fragile X syndrome
M Hawkins, J Boyle, KE Wright, R Elles… - European Journal of …, 2011 - nature.com
Fragile X syndrome is the most common inherited form of mental retardation. It is caused by
expansion of a trinucleotide (CGG) n repeat sequence in the 5′ untranslated region of the …
expansion of a trinucleotide (CGG) n repeat sequence in the 5′ untranslated region of the …
Skewed X inactivation of the normal allele in fully mutated female carriers determines the levels of FMRP in blood and the fragile X phenotype
R Martínez, V Bonilla-Henao, A Jiménez, M Lucas… - Molecular …, 2005 - Springer
Background: The variable phenotype in female carriers of a full mutation is explained in part
by non-random X-chromosome inactivation. The molecular diagnosis of fragile X syndrome …
by non-random X-chromosome inactivation. The molecular diagnosis of fragile X syndrome …
The siblings with ischemic stroke study (SWISS): a progress report
JF Meschia, BM Kissela, TG Brott… - Clinical medicine & …, 2006 - Marshfield Clinic
There is increasing evidence that genetic factors are associated with ischemic stroke,
including multiple recent reports of association with the gene PDE4D, encoding …
including multiple recent reports of association with the gene PDE4D, encoding …
[图书][B] CpG islands of the vitamin D receptor gene: differential methylation and tuberculosis predisposition
C Andraos - 2010 - search.proquest.com
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (M.
tuberculosis). TB is a multifactorial disease, influenced by both environmental and genetic …
tuberculosis). TB is a multifactorial disease, influenced by both environmental and genetic …
Regulación genética y epigenética de la producción de IFN-γ y su asociación con la susceptibilidad a la tuberculosis
GI Álvarez - 2016 - ridaa.unq.edu.ar
La tuberculosis, causada por el patógeno Mycobacterium tuberculosis, a pesar de ser una
enfermedad curable, continúa siendo un grave problema para la salud mundial causando …
enfermedad curable, continúa siendo un grave problema para la salud mundial causando …