BDNF as a promising therapeutic agent in Parkinson's disease

E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

Actions of brain-derived neurotrophin factor in the neurogenesis and neuronal function, and its involvement in the pathophysiology of brain diseases

T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2018 - mdpi.com
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …

[HTML][HTML] Effects of physical exercise on plasma brain-derived neurotrophic factor in neurodegenerative disorders: a systematic review and meta-analysis of …

D Ruiz-Gonzalez, A Hernandez-Martinez… - Neuroscience & …, 2021 - Elsevier
Neurodegenerative disorders are associated with reduced levels of brain-derived
neurotrophic factor (BDNF). We aimed to assess the effect of exercise interventions on …

[HTML][HTML] The contribution of physical exercise to brain resilience

RM Arida, L Teixeira-Machado - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
Increasing attention has been given to understanding resilience to brain diseases, often
described as brain or cognitive reserve. Among the protective factors for the development of …

Roles of myokines in exercise-induced improvement of neuropsychiatric function

S Kim, JY Choi, S Moon, DH Park, HB Kwak… - … -European Journal of …, 2019 - Springer
Exercise is a well-known non-pharmacological intervention to improve brain functions,
including cognition, memory, and motor coordination. Contraction of skeletal muscles during …

Does exercise attenuate disease progression in people with Parkinson's disease? A systematic review with meta-analyses

JA Li, MB Loevaas, C Guan, L Goh… - … and Neural Repair, 2023 - journals.sagepub.com
Introduction Exercise has many benefits for people with Parkinson's disease (PD) and has
been suggested to modify PD progression, but robust evidence supporting this is lacking …

A cortical pathogenic theory of Parkinson's disease

G Foffani, JA Obeso - Neuron, 2018 - cell.com
In Parkinson's disease, the progressive neurodegeneration of nigrostriatal dopaminergic
neurons in the substantia nigra pars compacta (SNc) is associated with classic motor …

Exercise-induced increase in blood-based brain-derived neurotrophic factor (BDNF) in people with multiple sclerosis: A systematic review and meta-analysis of …

P Shobeiri, A Karimi, S Momtazmanesh, AL Teixeira… - PloS one, 2022 - journals.plos.org
Background Exercise training may affect the blood levels of brain-derived neurotrophic
factor (BDNF), but meta-analyses have not yet been performed comparing pre-and post …

Exercise for Parkinson's disease

MKY Mak, ISK Wong-Yu - International review of neurobiology, 2019 - Elsevier
Parkinson's disease is the second most common neurodegenerative disease with a
prevalence rate of 1–2 per 1000 of the population worldwide. Pharmacological management …

Plasma levels of brain-derived neurotrophic factor in patients with Parkinson disease: a systematic review and meta-analysis

F Rahmani, A Saghazadeh, M Rahmani, AL Teixeira… - Brain research, 2019 - Elsevier
Background Brain-derived neurotrophic factor (BDNF) is an abundant neurotrophin in the
adult brain. Serum BDNF levels might be used as a proxy for its central expression …