Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …

BACKGROUND. Adrenal aldosterone excess is the most common cause of secondary
hypertension and is associated with increased cardiovascular morbidity. However, adverse …

Primary aldosteronism affects≈ 5% to 10% of hypertensive patients and has unilateral and
bilateral forms. Most unilateral primary aldosteronism is caused by computed tomography …

Primary aldosteronism (PA), a common cause of high blood pressure (BP), induces left
ventricular (LV) hypertrophy and an excess rate of cardiovascular events. Whether its …

The vast majority of hypertensive patients are never sought for a cause of their high blood
pressure, ie for a 'secondary'form of arterial hypertension. This under detection explains why …

Background: Computed tomography (CT), magnetic resonance imaging (MRI), and adrenal
vein sampling (AVS) are used to distinguish unilateral from bilateral increased aldosterone …

Context: In patients who seek surgical cure of primary aldosteronism (PA), The Endocrine
Society Guidelines recommend the use of adrenal vein sampling (AVS), which is invasive …

There have been several clinical studies examining the factors associated with
cardiovascular disease (CVD) in patients with primary aldosteronism (PA); however, their …

Primary aldosteronism is the most common form of secondary hypertension. Somatic
mutations in KCNJ5, ATP1A1, ATP2B3, and CACNA1D have been described in aldosterone …

Primary aldosteronism is the most common and curable form of secondary arterial
hypertension. We performed whole-exome sequencing in patients with early-onset primary …