Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem
without effective therapy and is a significant and frequent cause of morbidity and mortality …

Ischemia/reperfusion injury (IRI) is caused by a sudden temporary impairment of the blood
flow to the particular organ. IRI usually is associated with a robust inflammatory and …

Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …

We report the identification of rat and human cDNAs for a type 1 membrane protein that
contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is named …

In land mammals, a major task of the kidney is to reabsorb water to allow survival in a dry
environment. Water conservation is enhanced by the renal medulla, which concentrates the …

Cisplatin remains a major antineoplastic drug for the treatment of solid tumors. Its chief dose-
limiting side effect is nephrotoxicity, which evolves slowly and predictably after initial and …

CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …

Intravascular haemolysis is a fundamental feature of chronic hereditary and acquired
haemolytic anaemias, including those associated with haemoglobinopathies, complement …

The purpose of these studies was to examine the role of cytokines in the pathogenesis of
cisplatin nephrotoxicity. Injection of mice with cisplatin (20 mg/kg) led to severe renal failure …

Delayed graft function is a form of acute renal failure resulting in post-transplantation
oliguria, increased allograft immunogenicity and risk of acute rejection episodes, and …