[HTML][HTML] Stress, epigenetics, and aging: unraveling the intricate crosstalk

Z Wu, J Qu, W Zhang, GH Liu - Molecular Cell, 2024 - cell.com
Aging, as a complex process involving multiple cellular and molecular pathways, is known to
be exacerbated by various stresses. Because responses to these stresses, such as oxidative …

Educational mobility, pace of aging, and lifespan among participants in the Framingham heart study

GHJ Graf, AE Aiello, A Caspi, M Kothari, H Liu… - JAMA Network …, 2024 - jamanetwork.com
Importance People who complete more education live longer lives with better health. New
evidence suggests that these benefits operate through a slowed pace of biological aging. If …

From premature birth to premature kidney disease: does accelerated aging play a role?

KR Sanderson, C Wekon-Kemeni, JR Charlton - Pediatric Nephrology, 2024 - Springer
As the limits of fetal viability have increased over the past 30 years, there has been a
growing body of evidence supporting the idea that chronic disease should be taken into …

Does biological age mediate the relationship between childhood adversity and depression? Insights from the Detroit Neighborhood Health Study

RAM Martinez, AG Howard… - Social Science & …, 2024 - Elsevier
The link between childhood adversity and adulthood depression is well-established;
however, the underlying mechanisms are still being explored. Recent research suggests …

Statistical and conceptual considerations in socioepigenomics research on childhood adversity and epigenetic aging

EC Dunn, AJ Simpkin, E Walton - JAMA Network Open, 2023 - jamanetwork.com
Applications of epigenetic clocks to health questions have proliferated over the past decade,
particularly as a means of understanding disease etiology. Epigenetic clocks are aggregate …

Associations between epigenetic age acceleration and longitudinal measures of psychosocioeconomic stress and status

KE Markon, F Mann, C Freilich, S Cole… - Social Science & …, 2024 - Elsevier
Relationships between epigenetic aging markers and psychosocial variables such as
socioeconomic status and stress have been well-documented, but are often examined cross …

Mendelian randomization identifies causal effects of major depressive disorder on accelerated aging

Z Wang, Y Dou, L Chen, W Feng, Y Zou, J Xiao… - Journal of Affective …, 2024 - Elsevier
Background Evidence links major depressive disorder (MDD) with aging, but it's unclear if
MDD accelerates aging and what factors mediate this transition. Methods Two-sample …

Educational Mobility, the Pace of Biological Aging, and Lifespan in the Framingham Heart Study

G Graf, AE Aiello, A Caspi, M Kothari, H Liu, TE Moffitt… - medRxiv, 2023 - medrxiv.org
Importance: People who complete more education live longer lives with better health. New
evidence suggests that these benefits operate through a slowed pace of biological aging. If …

Better Life's Essential 8 contributes to slowing the biological aging process: a cross-sectional study based on NHANES 2007–2010 data

D Wu, C Qu, P Huang, X Geng, J Zhang… - Frontiers in Public …, 2024 - frontiersin.org
Objective To investigate the relationship between Life's Essential 8 (LE8) and Phenotypic
Age Acceleration (PhenoAgeAccel) in United States adults and to explore the impact of LE8 …

Understanding the role of childhood nurture, abuse, and stability on gestational diabetes in the Coronary Artery Risk Development in Young Adults study (CARDIA)

KK Stanhope, EP Gunderson, SF Suglia, SL Boulet… - Annals of …, 2024 - Elsevier
Background To estimate associations between facets of the maternal childhood family
environment with gestational diabetes (GDM) and to test mediation by pre-pregnancy waist …