The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

Bone tissue engineering is a promising approach that uses seed-cell-scaffold drug delivery
systems to reconstruct bone defects caused by trauma, tumors, or other diseases (eg …

Diet and lifestyle factors greatly affect health and susceptibility to diseases, including cancer.
Stem cells' functions, including their ability to divide asymmetrically, set the rules for tissue …

Background Dementia is prevalent in aged populations and is associated with disability and
distress for those affected. Therapeutic benefits of drugs targeting dementia are small …

Silk fibroin (SF) as a natural polymer has a long history of application in various regenerative
medicine fields, but there are still many shortcomings in silk fibroin for using as nerve …

Individuals with type 2 diabetes mellitus (T2DM) have an increased risk of bone metabolic
disorders and bone fracture due to disease progression and clinical treatment. The effect of …

Bone formation and homeostasis are controlled by environmental factors and endocrine
regulatory cues that initiate intracellular signaling pathways capable of modulating gene …

Based on the evidence of a significant communication and connection pathway between the
bone and immune systems, a new science has emerged: osteoimmunology. Indeed, the …

Aging and age-associated diseases (AADs) are growing risk factors in societies worldwide.
During aging, there is an accumulation of excessive oxygen free radicals [reactive oxygen …

Oxygen free radicals [reactive oxygen species (ROS)] and nitrogen free radicals [reactive
nitrogen species (RNS)] are generated by mitochondria during adenosine triphosphate …