[HTML][HTML] Dynamics of tuberculosis infection in various populations during the 19th and 20th century: The impact of conservative and pharmaceutical treatments

KL Holloway-Kew, M Henneberg - Tuberculosis, 2023 - Elsevier
Humans and Mycobacterium tuberculosis have co-evolved together for thousands of years.
Many individuals are infected with the bacterium, but few show signs and symptoms of …

Multimorbidity, Treatment, and Determinants among Chronic Patients Attending Primary Health Facilities in Tshwane, South Africa

TW Mkhwanazi, P Modjadji, K Mokgalaboni, S Madiba… - Diseases, 2023 - mdpi.com
The growing burden of non-communicable diseases amidst the largest burden of HIV in
South Africa leads to disease combinations of multimorbidity with the complexity of care. We …

A pathway to strengthening open science: comments on the draft South African Ethics in Health Research Guidelines

A Gooden - Frontiers in Pharmacology, 2024 - frontiersin.org
The recently released draft South African Ethics in Health Research Guidelines: Principles,
Processes and Structures (Draft Guidelines) by the National Health Research Ethics Council …

Drivers of sex differences in the South African adult tuberculosis incidence and mortality trends, 1990–2019

M Kubjane, M Cornell, M Osman, A Boulle… - Scientific Reports, 2023 - nature.com
Males have higher tuberculosis incidence and mortality rates than females. This study aimed
to assess how sex differences in tuberculosis incidence and mortality could be explained by …

Tuberculosis testing patterns in South Africa to identify groups that would benefit from increased investigation

AN Shapiro, L Scott, H Moultrie, KR Jacobson, J Bor… - Scientific Reports, 2023 - nature.com
Abstract The National Health Laboratory Service (NHLS) collects all public health laboratory
test results in South Africa, providing a cohort from which to identify groups, by age, sex, HIV …

A model-based approach to estimating the prevalence of disease combinations in South Africa

LF Johnson, R Kassanjee, N Folb, S Bennett… - BMJ Global …, 2024 - gh.bmj.com
Background The development of strategies to better detect and manage patients with
multiple long-term conditions requires estimates of the most prevalent condition …

Prevalence and association of HIV and tuberculosis status in older adults in South Africa: an urgent need to escalate the scientific and political attention to aging and …

ME Akokuwebe, GN Osuafor… - Frontiers in Public Health, 2024 - frontiersin.org
Objectives This study examined the prevalence and sociodemographic factors among older
adults with HIV and TB status in South Africa. Methods This data was cross-sectional and …

For Tuberculosis, Not “To Screen or Not to Screen?” but “Who?” and “How?”

MR Farhat, KR Jacobson - Clinical Infectious Diseases, 2024 - academic.oup.com
Active case finding leveraging new molecular diagnostics and chest X-rays with automated
interpretation algorithms is increasingly being developed for high-risk populations to drive …

'Not taking medications and taking medication, it was the same thing:'Perspectives of antiretroviral therapy among people hospitalised with advanced HIV disease

M Loveday, S Hlangu, P Manickchund, T Govender… - 2024 - researchsquare.com
Background Despite HIV's evolution to a chronic disease, the burden of advanced HIV
disease (AHD) remains high among PLHIV on ART, due in part to treatment interruptions. TB …

Modelling the South African tuberculosis epidemic: the effect of HIV, sex differences, and the impact of interventions

M Kubjane - 2023 - open.uct.ac.za
Abstract The South African tuberculosis (TB) epidemic is driven mainly by HIV, and the TB
disease burden is greater in males than females. Additional factors that drive the epidemic …