[HTML][HTML] The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

[HTML][HTML] The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as …

H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …

[HTML][HTML] Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course

J Muri, V Cecchinato, A Cavalli, AA Shanbhag… - Nature …, 2023 - nature.com
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse
symptoms, which can persist for months. While antiviral antibodies are protective, those …

Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19

P Laurent, C Yang, AF Rendeiro… - Science …, 2022 - science.org
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients
with COVID-19 by producing a cytokine storm, which correlates with increased lethality …

[HTML][HTML] The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress …

MC Cesta, M Zippoli, C Marsiglia, EM Gavioli… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …

[HTML][HTML] Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality

T Nakanishi, S Pigazzini, F Degenhardt… - The Journal of …, 2021 - Am Soc Clin Investig
Background There is considerable variability in COVID-19 outcomes among younger adults,
and some of this variation may be due to genetic predisposition. Methods We combined …

[HTML][HTML] Persistent Oxidative Stress and Inflammasome Activation in CD14highCD16 Monocytes From COVID-19 Patients

SL Lage, EP Amaral, KL Hilligan, E Laidlaw… - Frontiers in …, 2022 - frontiersin.org
The poor outcome of the coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is
associated with systemic hyperinflammatory response and immunopathology. Although …

[HTML][HTML] Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …

R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
Severe COVID-19 is characterized by a “cytokine storm”, the mechanism of which is not yet
understood. I propose that cytokine storms result from synergistic interactions among Toll …

Mortality among adults with cancer undergoing chemotherapy or immunotherapy and infected with COVID-19

C Várnai, C Palles, R Arnold, HM Curley… - JAMA network …, 2022 - jamanetwork.com
Importance Large cohorts of patients with active cancers and COVID-19 infection are
needed to provide evidence of the association of recent cancer treatment and cancer type …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …