The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …
The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress syndrome
MC Cesta, M Zippoli, C Marsiglia, EM Gavioli… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …
Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
J Muri, V Cecchinato, A Cavalli, AA Shanbhag… - Nature …, 2023 - nature.com
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse
symptoms, which can persist for months. While antiviral antibodies are protective, those …
symptoms, which can persist for months. While antiviral antibodies are protective, those …
Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients
with COVID-19 by producing a cytokine storm, which correlates with increased lethality …
with COVID-19 by producing a cytokine storm, which correlates with increased lethality …
The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as potential …
H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …
The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
T Nakanishi, S Pigazzini, F Degenhardt… - The Journal of …, 2021 - Am Soc Clin Investig
Background There is considerable variability in COVID-19 outcomes among younger adults,
and some of this variation may be due to genetic predisposition. Methods We combined …
and some of this variation may be due to genetic predisposition. Methods We combined …
Coinfection with SARS-CoV-2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4+ T Cell Responses
Given the current coronavirus disease 2019 (COVID-19) pandemic, coinfection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus (IAV) is a …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus (IAV) is a …
Persistent Oxidative Stress and Inflammasome Activation in CD14highCD16− Monocytes From COVID-19 Patients
SL Lage, EP Amaral, KL Hilligan, E Laidlaw… - Frontiers in …, 2022 - frontiersin.org
The poor outcome of the coronavirus disease-2019 (COVID-19), caused by SARS-CoV-2, is
associated with systemic hyperinflammatory response and immunopathology. Although …
associated with systemic hyperinflammatory response and immunopathology. Although …
Innate receptor activation patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel …
R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
Severe COVID-19 is characterized by a “cytokine storm”, the mechanism of which is not yet
understood. I propose that cytokine storms result from synergistic interactions among Toll …
understood. I propose that cytokine storms result from synergistic interactions among Toll …