The endocrine role of bone: Novel functions of bone-derived cytokines

H Wang, X Zheng, Y Zhang, J Huang, W Zhou… - Biochemical …, 2021 - Elsevier
Bone-derived cytokines refer to various proteins and peptides that are released from the
skeleton and can distribute in organisms to regulate homeostasis by targeting many organs …

Bioinformatics Analysis of the Mechanisms of Diabetic Nephropathy via Novel Biomarkers and Competing Endogenous RNA Network

M Guo, Y Dai, L Jiang, J Gao - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) is one of the common chronic complications of diabetes with
unclear molecular mechanisms, which is associated with end-stage renal disease (ESRD) …

Adiponectin inhibits D‑gal‑induced cardiomyocyte senescence via AdipoR1/APPL1

R Liu, J Meng, D Lou - Molecular Medicine Reports, 2021 - spandidos-publications.com
The aim of the present study was to examine whether adiponectin could inhibit
cardiomyocyte senescence induced by D‑galactose (D‑gal), and whether it functioned via …

Development of biomarkers and molecular therapy based on inflammatory genes in diabetic nephropathy

AK Maiti - International Journal of Molecular Sciences, 2021 - mdpi.com
Diabetic Nephropathy (DN) is a debilitating consequence of both Type 1 and Type 2
diabetes affecting the kidney and renal tubules leading to End Stage Renal Disease …

Effects of adiponectin on T2DM and glucose homeostasis: a mendelian randomization study

Z Chen, Y Bai, X Long, Q Luo, Z Wen, Y Li… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Purpose The associations of adiponectin with type 2 diabetes mellitus (T2DM), glucose
homeostasis (including β-cell function index (HOMA-β), insulin resistance (HOMA-IR) …

ADIPOQ rs2241766 Gene Polymorphism and Predisposition to Diabetic Kidney Disease

Q Han, W Geng, D Zhang, G Cai… - Journal of Diabetes …, 2020 - Wiley Online Library
Background. This meta‐analysis was performed to obtain a more comprehensive estimation
of the role of the single nucleotide polymorphism (SNP) rs2241766 in the ADIPOQ gene in …

Azithromycin inhibited oxidative stress and apoptosis of high glucose‐induced podocytes by inhibiting STAT1 pathway

YW Xing, KZ Liu - Drug Development Research, 2021 - Wiley Online Library
Azithromycin (AZM) has a therapeutic effect on diabetes, but there is no report on whether
AZM has a therapeutic effect on diabetic nephropathy (DN) and its specific mechanism. Cell …

[PDF][PDF] Metabolic cardio-and reno-protective effects of empagliflozin in a prediabetic rat model.

M Huttl, I Markova, D Miklankova… - Journal of Physiology …, 2020 - jpp.krakow.pl
The mechanisms behind the cardiovascular and renal benefits of empagliflozin is not fully
understood. The positive impact of the medication on cardiovascular mortality can not be …

Deterioration of diabetic nephropathy via stimulating secretion of cytokines by atrial natriuretic peptide

C Liu, Q Li, X Feng, J Zhu, Q Li - BMC Endocrine Disorders, 2021 - Springer
Background Atrial natriuretic peptide (ANP) is a cardiovascular and metabolic hormone that
has been identified recently as being associated with chronic kidney disease (CKD) without …

Whole transcriptome mapping reveals the lncRNA regulatory network of TFP5 treatment in diabetic nephropathy

H Luo, L Yang, G Zhang, X Bao, D Ma, B Li, L Cao… - Genes & Genomics, 2024 - Springer
Background TFP5 is a Cdk5 inhibitor peptide, which could restore insulin production.
However, the role of TFP5 in diabetic nephropathy (DN) is still unclear. Objective This study …