The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

Recent advances in biomaterials, microfabrication, microfluidics, and cell biology have led to
the development of organ-on-a-chip devices that can reproduce key functions of various …

This report is the second part of a comprehensive two-part series aimed at reviewing an
extensive and diverse toolkit of novel methods to explore brain health and function. While …

Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa.
Sleep-inducing inflammatory molecules are activated by increased waking activity and …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Research has suggested a number of beneficial effects arising from the consumption of
dietary flavonoids, found in foods such as cocoa, apples, tea, citrus fruits and berries on …

Background Detailed information on the temperature dependence of tissue thermophysical
and mechanical properties is pivotal for the optimal implementation of mathematical models …

Characterizing blood flow dynamics in vivo is critical to understanding the function of the
vascular network under physiological and pathological conditions. Existing methods for …

The cerebral vasculature is made up of highly specialized structures that assure constant
brain perfusion necessary to meet the very high demand for oxygen and glucose by neurons …

Subarachnoid hemorrhage (SAH) is a devastating stroke subtype with a high rate of
mortality and morbidity. The poor clinical outcome can be attributed to the biphasic course of …