Aims/hypothesis The aim of this study was to use Mendelian randomisation (MR) to identify
the causal risk factors for type 2 diabetes. Methods We first conducted a review of meta …

Passive permeability is a key property in drug disposition and delivery. It is critical for
gastrointestinal absorption, brain penetration, renal reabsorption, defining clearance …

We examined whether specifically statins, of the major lipid modifiers (statins, proprotein
convertase subtilisin/kexin type 9 (PCSK9) inhibitors and ezetimibe) have pleiotropic effects …

Background ABO blood group is associated with differences in lifespan, cardiovascular
disease, and some cancers, for reasons which are incompletely understood. To gain sex …

Objectives Statins appear to have pleiotropic effects. We examined whether specifically
statins, of the major lipid modifiers, operate on ischemic heart disease (IHD) via …

O desenvolvimento de vacinas envolve a necessidade de se controlar todos os eventos
adversos, visando monitorar a segurança do produto sob investigação de forma ágil e …

The development of vaccines involves the need to control all adverse events, in order to
monitor product safety under investigation in an agile and accurate manner. Objective: This …