Genome-wide association studies (GWAS) have reported substantial genomic loci
significantly associated with clinical risk of bipolar disorder (BD), and studies combining …

Genetic variants are traditionally known to shape the susceptibility to neuropsychiatric
disorders. An increasing number of studies indicate that remodeling of the gut microbiome …

Genome-wide association studies (GWASs) have identified multiple risk loci for bipolar
disorder (BD). However, pinpointing functional (or causal) variants in the reported risk loci …

Bipolar disorder (BD) is a neuropsychiatric mood disorder manifested by recurrent episodes
of mania and depression. More than half of BD patients are non-responsive to lithium, the …

Bipolar disorder (BD) and obesity are highly comorbid. We previously performed a genome-
wide association study (GWAS) for BD risk accounting for the effect of body mass index …

Inhibition of Glycogen synthase kinase 3 (GSK3) is a popular explanation for the effects of
lithium ions on mood regulation in bipolar disorder and other mental illnesses, including …

It has been hypothesized that a higher genetic risk of bipolar disorder (BD) is associated
with greater creativity. Given the clinical importance of bipolar disorder and the importance …

Aims/hypothesis Psychiatric disorders, such as schizophrenia (SCZ), major depressive
disorder (MDD) and bipolar disorder (BPD), are highly comorbid with type 2 diabetes …

Functional changes of white matter are largely unexplored in patients with psychiatric
disorders. This study examined white matter dysfunctions common in four major psychiatric …

Aim: Genome-wide association studies (GWAS) analyses have revealed genetic evidence of
bipolar disorder (BD), but little is known about the genetic structure of BD subtypes. We …