Long non-coding RNAs: a new frontier in the study of human diseases

X Shi, M Sun, H Liu, Y Yao, Y Song - Cancer letters, 2013 - Elsevier
With the development of whole genome and transcriptome sequencing technologies, long
noncoding RNAs (lncRNAs) have received increased attention. Multiple studies indicate that …

Genetic and epigenetic aspects of breast cancer progression and therapy

S Byler, S Goldgar, S Heerboth, M Leary… - Anticancer …, 2014 - ar.iiarjournals.org
Although breast cancer is a heterogeneous disease that is challenging to characterize and
treat, the recent explosion of genetic and epigenetic research may help improve these …

Inhibition of histone lysine-specific demethylase 1 elicits breast tumor immunity and enhances antitumor efficacy of immune checkpoint blockade

Y Qin, SN Vasilatos, L Chen, H Wu, Z Cao, Y Fu… - Oncogene, 2019 - nature.com
Immunotherapy strategies have been emerging as powerful weapons against cancer. Early
clinical trials reveal that overall response to immunotherapy is low in breast cancer patients …

[HTML][HTML] Phytoestrogens and breast cancer: In vitro anticancer activities of isoflavones, lignans, coumestans, stilbenes and their analogs and derivatives

P Basu, C Maier - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Breast cancer is one of the leading causes of cancer-related morbidity and mortality among
women worldwide. Phytoestrogens, plant-derived polyphenols that structurally and …

[HTML][HTML] Cadmium and breast cancer–current state and research gaps in the underlying mechanisms

K Tarhonska, M Lesicka, B Janasik, J Roszak… - Toxicology Letters, 2022 - Elsevier
Cadmium (Cd), a heavy metal with strong carcinogenic properties has been linked with
breast cancer risk. Epidemiological data on the association between Cd exposure and …

The genomic landscape of breast cancer as a therapeutic roadmap

MJ Ellis, CM Perou - Cancer discovery, 2013 - AACR
The application of high-throughput techniques to profile DNA, RNA, and protein in breast
cancer samples from hundreds of patients has profoundly increased our knowledge of the …

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

Q Feng, Z Zhang, MJ Shea, CJ Creighton, C Coarfa… - Cell research, 2014 - nature.com
Tamoxifen has been a frontline treatment for estrogen receptor alpha (ERα)-positive breast
tumors in premenopausal women. However, resistance to tamoxifen occurs in many …

[HTML][HTML] Female breast cancer and alcohol consumption: a review of the literature

C Scoccianti, B Lauby-Secretan, PY Bello… - American journal of …, 2014 - Elsevier
Context Consumption of alcoholic beverages is one of the single most important known and
modifiable risk factor for human cancer. Among women, breast cancer is the most common …

Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer

AB Crujeiras, A Díaz-Lagares, MC Carreira… - Free radical …, 2013 - Taylor & Francis
Diabetes mellitus and breast cancer are two important health problems. Type 2 diabetes
(T2DM) and obesity are closely linked with both being associated with breast cancer …

Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancer

X Shi, Z Liu, Z Liu, X Feng, F Hua, X Hu, B Wang… - …, 2018 - thelancet.com
Background NSCLC (non-small-cell lung cancer) is the leading cause of cancer-related
mortality worldwide. Both epigenetic and genetic changes contribute to the initiation …