A real-world pharmacovigilance study on cardiovascular adverse events of tisagenlecleucel using machine learning approach

J Jung, JH Kim, JH Bae, SS Woo, H Lee, JY Shin - Scientific Reports, 2024 - nature.com
Chimeric antigen receptor T-cell (CAR-T) therapies are a paradigm-shifting therapeutic in
patients with hematological malignancies. However, some concerns remain that they may …

Predictive Modeling of Drug‐Related Adverse Events with Real‐World Data: A Case Study of Linezolid Hematologic Outcomes

A Patel, SB Doernberg, T Zack, AJ Butte… - Clinical …, 2024 - Wiley Online Library
Electronic health records (EHRs) provide meaningful knowledge of drug‐related adverse
events (AEs) that are not captured in standard drug development and postmarketing …

Unveiling nonlinear effects of built environment attributes on urban heat resilience using interpretable machine learning

Q Liu, J Wang, B Bai - Urban Climate, 2024 - Elsevier
Built environment attributes (BEAs) play a significant role in influencing urban heat
resilience (UHR). Previous research has examined the correlations and nonlinear …

Prediction of antidepressant side effects in the Genetic Link to Anxiety and Depression Study

D Li, Y Lin, HL Davies, JK Zvrskovec, R Wang… - medRxiv, 2024 - medrxiv.org
Antidepressants are the most common treatment for moderate or severe depression. Side
effects are crucial indicators for antidepressants, but their expression varies widely among …

Advanced Machine Learning for Risk Assessment of Cardiovascular Disease

Y Mahajan, E Arshdeep, D Saxena - … Conference on Integrated …, 2023 - ieeexplore.ieee.org
This research carried out a thorough analysis of machine learning algorithms that are used
to predict cardiovascular disease. Using a large dataset with a variety of patient variables …

A Systemic Review of Machine Learning Approaches for Adverse Drug Reaction Detection: Novel Perspective and Challenges

S Basnet, A Nihal, KS Sijina, NK Seru… - Journal of Pharma Insights …, 2023 - jopir.in
Medication errors significantly impact patient treatment outcomes, necessitating the
integration of modern technologies for improved detection and prevention. This review …