Advances in genomics have enabled the development of polygenic scores (PGS),
sometimes called polygenic risk scores, in the context of multifactorial diseases and …

Polygenic scores (PGS) are primed for use in personalized risk assessments for common,
complex conditions and population health screening. Although there is growing evidence …

Psychiatric polygenic risk scores (PRS) have potential utility in psychiatric care and
prevention, but there are concerns about their implementation. We surveyed 960 US‐based …

Advances in human genetics raise many social and ethical issues. The application of
genomic technologies to healthcare has raised many questions at the level of the individual …

Research in pharmacogenomics and precision medicine has recently introduced the
concept of Polygenic Scores (PGSs), namely, indexes that aggregate the effects that many …

In different species, embryonic aneuploidies and genome-wide errors are a major cause of
developmental failure. The increasing number of equine embryos being produced …

Preimplantation genetic testing (PGT) involves testing embryos created through in vitro
fertilization for the presence of hereditary genetic disorders and chromosome abnormalities …

BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …

Schizophrenia is a highly heritable, severe mental illness characterized by hallucinations,
delusions, social withdrawal, and cognitive dysfunction present in∼ 1% of populations …

Research question Has acceptance of heritable genome editing (HGE) and whole genome
sequencing for preimplantation genetic testing (PGT-WGS) of human embryos changed after …