[HTML][HTML] CD4 T-cell subsets and the pathophysiology of inflammatory bowel disease

R Gomez-Bris, A Saez, B Herrero-Fernandez… - International journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is an umbrella term for the chronic immune-mediated
idiopathic inflammation of the gastrointestinal tract, manifesting as Crohn's disease (CD) or …

Pharmacologic effects approach of essential oils and their components on respiratory diseases

J Li, W Chen, H Liu, H Liu, S Xiang, F You… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Essential oils (EOs) are concentrated
hydrophobic liquids with volatility and a unique aroma. Formed by aromatic plants as …

[HTML][HTML] Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

JK Kim, BT Tierney, EG Overbey, E Dantas… - Nature …, 2024 - nature.com
Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …

[HTML][HTML] Causal relationships of metabolites with allergic diseases: a trans-ethnic Mendelian randomization study

J Tu, J Wen, Q Luo, X Li, D Wang, J Ye - Respiratory Research, 2024 - Springer
Background Allergic diseases exert a considerable impact on global health, thus
necessitating investigations into their etiology and pathophysiology for devising effective …

[HTML][HTML] Quercetin a promising functional food additive against allergic diseases: a comprehensive and mechanistic review

NN Najafi, N Armide, A Akbari, VB Rahimi… - Journal of Functional …, 2024 - Elsevier
The crucial roles of innate and acquired immunity in the pathogenesis of allergic diseases
have been well highlighted based on molecular mechanisms. Thus, the modulation of …

Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis

MM Alhasan, O Hölsken, C Duerr… - European Journal of …, 2023 - Wiley Online Library
Antibiotic use during pregnancy is associated with increased asthma risk in children. Since
approximately 25% of women use antibiotics during pregnancy, it is important to identify the …

Aberrant expression of suppressor of cytokine signaling (SOCS) molecules contributes to the development of allergic diseases

A Jafarzadeh, P Chauhan, M Nemati… - Clinical & …, 2023 - Wiley Online Library
Suppressor of cytokine signalling (SOCS) proteins bind to certain cytokine receptors, Janus
kinases and signalling molecules to regulate signalling pathways, thus controlling immune …

Short-term administration of Qipian®, a mixed bacterial lysate, inhibits airway inflammation in ovalbumin-induced mouse asthma by modulating cellular, humoral and …

H Wang, F Tao, CY Li, GJ Yang, J Chen - Life Sciences, 2024 - Elsevier
Aims Qipian® is a commercialized agent composed of extracts of three genera of
commensal bacteria, and its mechanism of action on asthma is unclear. This study aimed to …

[HTML][HTML] Sitagliptin Induces Tolerogenic Human Dendritic Cells

M Drakul, S Tomić, M Bekić, D Mihajlović… - International Journal of …, 2023 - mdpi.com
Sitagliptin, an anti-diabetic drug, is a dipeptidyl peptidase (DPP)-4/CD26 inhibitor with
additional anti-inflammatory and immunomodulatory properties. In this study, we …

Free fatty acid 3 receptor agonist AR420626 reduces allergic responses in asthma and eczema in mice

YJ Lee, SE Son, DS Im - International Immunopharmacology, 2024 - Elsevier
Free fatty acid 3 receptor (FFA3; previously GPR41) is a G protein-coupled receptor that
senses short-chain fatty acids and dietary metabolites produced by the gut microbiota. FFA3 …