Best practices in NMR metabolomics: Current state

R Powers, ER Andersson, AL Bayless, RB Brua… - TrAC Trends in …, 2023 - Elsevier
A literature survey was conducted to identify current practices used by NMR metabolomics
investigators when conducting and reporting their metabolomics studies. A total of 463 …

Multiplatform untargeted metabolomics

MJ Jeppesen, R Powers - Magnetic Resonance in Chemistry, 2023 - Wiley Online Library
Metabolomics samples like human urine or serum contain upwards of a few thousand
metabolites, but individual analytical techniques can only characterize a few hundred …

Metabolome-wide mendelian randomization assessing the causal relationship between blood metabolites and bone mineral density

S Chen, W He - Calcified Tissue International, 2023 - Springer
Mounting evidence has supported osteoporosis (OP) as a metabolic disorder. Recent
metabolomics studies have discovered numerous metabolites related to bone mineral …

[HTML][HTML] Circulating metabolites as potential biomarkers for the early detection and prognosis surveillance of gastrointestinal cancers

G Song, L Wang, J Tang, H Li, S Pang, Y Li, L Liu, J Hu - Metabolomics, 2023 - Springer
Background and aims Two of the most lethal gastrointestinal (GI) cancers, gastric cancer
(GC) and colon cancer (CC), are ranked in the top five cancers that cause deaths worldwide …

[HTML][HTML] A metabolites merging strategy (MMS): harmonization to enable studies' intercomparison

H Villalba, M Llambrich, J Gumà, J Brezmes… - Metabolites, 2023 - mdpi.com
Metabolomics encounters challenges in cross-study comparisons due to diverse metabolite
nomenclature and reporting practices. To bridge this gap, we introduce the Metabolites …

Potential Metabolite Biomarkers of Multiple Sclerosis from Multiple Biofluids

F Bhinderwala, HE Roth, M Filipi, S Jack… - ACS Chemical …, 2024 - ACS Publications
Multiple sclerosis (MS) is a chronic and progressive neurological disorder without a cure, but
early intervention can slow disease progression and improve the quality of life for MS …

Applications of chromatographic methods in metabolomics: A review

ST Ovbude, S Sharmeen, I Kyei, H Olupathage… - … of Chromatography B, 2024 - Elsevier
Chromatography is a robust and reliable separation method that can use various stationary
phases to separate complex mixtures commonly seen in metabolomics. This review …

Metabolomic data presents challenges for epidemiological meta-analysis: a case study of childhood body mass index from the ECHO consortium

N Prince, D Liang, Y Tan, A Alshawabkeh, EE Angel… - Metabolomics, 2024 - Springer
Introduction Meta-analyses across diverse independent studies provide improved
confidence in results. However, within the context of metabolomic epidemiology, meta …

An Optimized Method for LC–MS-Based Quantification of Endogenous Organic Acids: Metabolic Perturbations in Pancreatic Cancer

SK Jain, S Bansal, S Bansal, B Singh… - International Journal of …, 2024 - mdpi.com
Accurate and reliable quantification of organic acids with carboxylic acid functional groups in
complex biological samples remains a major analytical challenge in clinical chemistry …

Metabolic signature for a dysbiotic microbiome in the female genital tract: A systematic review and meta‐analysis

B Gill, I Schwecht, N Rahman, T Dhawan… - American Journal of …, 2023 - Wiley Online Library
Background The vaginal microbiome (VMB) is a critical determinant of reproductive health,
where a microbial shift towards a dysbiotic environment has implications for susceptibility to …