[HTML][HTML] Blood-brain barrier: from physiology to disease and back

MD Sweeney, Z Zhao, A Montagne… - Physiological …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Neuron–glia interactions in the pathophysiology of epilepsy

DC Patel, BP Tewari, L Chaunsali… - Nature Reviews …, 2019 - nature.com
Epilepsy is a neurological disorder afflicting~ 65 million people worldwide. It is caused by
aberrant synchronized firing of populations of neurons primarily due to imbalance between …

How does the COVID-19 cause seizure and epilepsy in patients? The potential mechanisms

F Nikbakht, A Mohammadkhanizadeh… - Multiple sclerosis and …, 2020 - Elsevier
The new coronavirus has spread throughout the world in a very short time and now has
become a pandemic. Most infected people have symptoms such as dry cough, dyspnea …

Development of novel therapeutics targeting the blood–brain barrier: from barrier to carrier

J Li, M Zheng, O Shimoni, WA Banks, AI Bush… - Advanced …, 2021 - Wiley Online Library
The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described
as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from …

[HTML][HTML] Astrocytes as guardians of neuronal excitability: mechanisms underlying epileptogenesis

QP Verhoog, L Holtman, E Aronica… - Frontiers in neurology, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

Blood-brain barrier permeability and physical exercise

MA Małkiewicz, A Szarmach, A Sabisz… - Journal of …, 2019 - Springer
In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

The association between inflammatory markers in blood and cerebrospinal fluid: A systematic review and meta-analysis

FAJ Gigase, E Smith, B Collins, K Moore… - Molecular …, 2023 - nature.com
Background Neuroinflammatory processes have been hypothesized to play a role in the
pathogenesis of psychiatric and neurological diseases. Studies on this topic often rely on …

Overview and introduction: the blood–brain barrier in health and disease

NJ Abbott, A Friedman - Epilepsia, 2012 - Wiley Online Library
This article introduces the special issue on “Blood–Brain Barrier and Epilepsy.” We review
briefly current understanding of the structure and function of the blood–brain barrier (BBB) …

Neuroimmune transcriptome changes in patient brains of psychiatric and neurological disorders

Y Chen, J Dai, L Tang, T Mikhailova, Q Liang, M Li… - Molecular …, 2023 - nature.com
Neuroinflammation has been implicated in multiple brain disorders but the extent and the
magnitude of change in immune-related genes (IRGs) across distinct brain disorders has not …

Impact of epigenetic reprogramming on antitumor immune responses in glioma

BL McClellan, S Haase, FJ Nunez… - The Journal of …, 2023 - Am Soc Clin Investig
Epigenetic remodeling is a molecular hallmark of gliomas, and it has been identified as a
key mediator of glioma progression. Epigenetic dysregulation contributes to gliomagenesis …