The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
Innate and acquired immunity responses are crucial for viral infection elimination. However,
genetic variations in coding genes may exacerbate the inflammation or initiate devastating …

Photobiomodulation improves serum cytokine response in mild to moderate COVID-19: The first randomized, double-blind, placebo controlled, pilot study

SM Marashian, M Hashemian, M Pourabdollah… - Frontiers in …, 2022 - frontiersin.org
Background Because the major event in COVID-19 is the release of pre-and inflammatory
cytokines, finding a reliable therapeutic strategy to inhibit this release, help patients manage …

Effects of selenoprotein extracts from Cardamine hupingshanensis on growth, selenium metabolism, antioxidant capacity, immunity and intestinal health in largemouth …

H Zhang, L Zhao, P Zhang, Y Xie, X Yao… - Frontiers in …, 2024 - frontiersin.org
This study aimed to assess the impact of dietary selenoprotein extracts from Cardamine
hupingshanensis (SePCH) on the growth, hematological parameters, selenium metabolism …

The role of nuclear factor Kappa B (NF-κB) in development and treatment of COVID-19

M Gudowska-Sawczuk, B Mroczko - International journal of molecular …, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus
Disease 19 (COVID-19), a disease that has affected more than 500 million people …

[HTML][HTML] Conjunctival epithelial cells resist productive SARS-CoV-2 infection

RM Jackson, CF Hatton, JS Spegarova, M Georgiou… - Stem Cell Reports, 2022 - cell.com
Conjunctival epithelial cells, which express viral-entry receptors angiotensin-converting
enzyme 2 (ACE2) and transmembrane protease serine type 2 (TMPRSS2), constitute the …

Severe acute respiratory syndrome coronavirus 2 infection in the stem cell transplant recipient− clinical spectrum and outcome

M Fernández-Ruiz, JM Aguado - Current Opinion in Infectious …, 2021 - journals.lww.com
Severe acute respiratory syndrome coronavirus 2 infection in... : Current Opinion in Infectious
Diseases Severe acute respiratory syndrome coronavirus 2 infection in the stem cell …

An Aloe‐Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D‐Galactose‐Induced Immunosenescence

M Yimam, T Horm, A O'Neal, P Jiao… - Journal of …, 2024 - Wiley Online Library
A decline in immune response, exhibited in the form of immunosenescence and
inflammaging, is an age‐associated disturbance of the immune system known to predispose …

Genotoxicity of cytokines at chemotherapy-induced 'storm'concentrations in a model of the human bone marrow

HSH Asurappulige, AD Thomas, HR Morse - Mutagenesis, 2023 - academic.oup.com
Donor cell leukaemia (DCL) is a complication of haematopoietic stem cell transplantation
where donated cells become malignant within the patient's bone marrow. As DCL …

Virlaza™ Inhibits Sars-COV-2-induced Inflammatory Response of Bronchial Epithelial Cells and Pulmonary Fibroblast

MAR Brandao-Rangel, D Melamed, A Silva-Reis… - medRxiv, 2021 - medrxiv.org
Abstract Coronavirus disease 2019 (COVID-19), which is currently a global public health
emergency and beyond vaccines as a prophylactic treatment, no specific and effective …