Hepatocyte infection by malaria sporozoites is a bottleneck in the life-cycle of Plasmodium
spp. including P. falciparum, which causes the most lethal form of malaria. Therefore …

In recent years, tissue‐resident memory T cells (TRM) have attracted significant attention in
the field of vaccine development. Distinct from central and effector memory T cells, TRM cells …

The efficacy of pre-erythrocytic stage malaria antigens or vaccine platforms is routinely
assessed in murine models challenged with Plasmodium sporozoites. Relative liver-stage …

Immunological memory is fundamental to maintain immunity against re-invading pathogens.
It is the basis for prolonged protection induced by vaccines and can be mediated by humoral …

Vaccines have been incredibly successful at stemming the morbidity and mortality of
infectious diseases worldwide. However, there are still no effective vaccines for many …

Tissue‐resident memory T (TRM) cells play a vital role in local immune protection against
infection and cancer. The location of TRM cells within peripheral tissues at sites of pathogen …

Attenuated sporozoites provide a valuable model for exploring protective immunity against
the malarial liver stage, guiding the design of highly efficient vaccines to prevent malaria …

Hepatitis C virus (HCV) is a significant contributor to the global disease burden, and
development of an effective vaccine is required to eliminate HCV infections worldwide …

Vaccine-induced sterilizing protection from infection by Plasmodium parasites, the
pathogens that cause malaria, will be essential in the fight against malaria as it would …

Introduction Tissue-resident memory T cells (TRM cells) are powerful mediators of protracted
adaptive immunity to infection in peripheral organs. Harnessing TRM cells through …