An effective vaccine against the Plasmodium parasite is likely to require the induction of
robust antibody and T cell responses. Chimeric virus-like particles are an effective vaccine …

Recently, a population of non-recirculating, tissue-resident memory CD8+ T cells has been
identified; cells that seems to act as key sentinels for invading microorganisms with …

Human immunodeficiency virus (HIV)-1 and hepatitis C virus (HCV) are major contributors to
the global disease burden with many experts recognizing the requirement of an effective …

In the last few decades, considerable efforts have been made toward the development of
efficient vaccines against malaria. Whole‐sporozoite (Wsp) vaccines, which induce efficient …

Introduction A highly efficacious and durable vaccine against malaria is an essential tool for
global malaria eradication. One of the promising strategies to develop such a vaccine is to …

Malaria, a disease caused by parasites of the Plasmodium genus, begins when Plasmodium-
infected mosquitoes inject malaria sporozoites while searching for blood. Sporozoites …

This chapter introduces the life cycle of malaria parasite, as well as immunopathogenesis,
diagnosis, and the prevention and treatment of malaria. It begins with the history of the …

The magnitude of the effector functions of memory T cells determines the consequences of
the protection against invading pathogens and tumor development or the pathogenesis of …

Despite promising progress in malaria vaccine development in recent years, an efficacious
subunit vaccine against Plasmodium falciparum remains to be licensed and deployed. Cell …

Malaria is a disease caused by Plasmodium parasites, resulting in over 200 million
infections and 400,000 deaths every year. A critical step of malaria infection is when …