Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity
S Belhimeur, S Briquet, R Peronet, J Pham… - Frontiers in …, 2023 - frontiersin.org
Introduction Plasmodium sporozoites (SPZ) inoculated by Anopheles mosquitoes into the
skin of the mammalian host migrate to the liver before infecting hepatocytes. Previous work …
skin of the mammalian host migrate to the liver before infecting hepatocytes. Previous work …
Hepatic inflammation confers protective immunity against liver stages of malaria parasite
M Grand, M Waqasi, C Demarta-Gatsi, Y Wei… - Frontiers in …, 2020 - frontiersin.org
Deciphering the mechanisms by which Plasmodium parasites develop inside hepatocytes is
an important step toward the understanding of malaria pathogenesis. We propose that the …
an important step toward the understanding of malaria pathogenesis. We propose that the …
Immunological characteristics of CD103+CD8+ Tc cells in the liver of C57BL/6 mouse infected with plasmodium NSM
F Shi, S Tang, D Chen, F Mo, J Li, C Fang, H Wei… - Parasitology …, 2023 - Springer
CD103 is an important marker of tissue-resident memory T cells (TRM) which play important
roles in fighting against infection. However, the immunological characteristics of CD103+ T …
roles in fighting against infection. However, the immunological characteristics of CD103+ T …
Screening of viral-vectored P. falciparum pre-erythrocytic candidate vaccine antigens using chimeric rodent parasites
To screen for additional vaccine candidate antigens of Plasmodium pre-erythrocytic stages,
fourteen P. falciparum proteins were selected based on expression in sporozoites or their …
fourteen P. falciparum proteins were selected based on expression in sporozoites or their …
Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Plasmodium Challenge in a Mouse Model
The need for a malaria vaccine is indisputable. A single vaccine for Plasmodium pre-
erythrocytic stages targeting the major sporozoite antigen circumsporozoite protein (CSP) …
erythrocytic stages targeting the major sporozoite antigen circumsporozoite protein (CSP) …
Fleet-Footed Soldiers: Circulating Memory CD8 T Cells Quickly Enter the Fray During Malarial and Bacterial Infection of the Liver
MN Lefebvre - 2023 - search.proquest.com
The highly vascularized liver may coordinate immune responses to infection or
inflammation, and this non-lymphoid tissue is also a key target of clinically relevant …
inflammation, and this non-lymphoid tissue is also a key target of clinically relevant …
Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and enhance protection of anti-CSP monoclonal antibodies
Vaccine-induced sterilizing protection from infection with the Plasmodium parasite, the
pathogen that causes malaria, will be an essential tool in the fight against malaria as it …
pathogen that causes malaria, will be an essential tool in the fight against malaria as it …
[PDF][PDF] Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants. Vaccines 2021, 9, 1072
Malaria—a parasite vector-borne disease—is a global health problem, and Plasmodium
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …
falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in …
Poxviral vaccines
Staib et al. Construction and Isolation of Recombinant MVA in chapter 7 of Methods in
Molecular Biology, vol. 269: Vaccinia Virus and Poxvirology: methods and protocols, Edited …
Molecular Biology, vol. 269: Vaccinia Virus and Poxvirology: methods and protocols, Edited …
Vaccine and assay development for nairoviral diseases
C Gilbride - 2022 - ora.ox.ac.uk
Emerging zoonotic diseases present a significant risk to global public health, as evidenced
by the ongoing COVID-19 pandemic. Nairoviruses are a genus of viruses, which include …
by the ongoing COVID-19 pandemic. Nairoviruses are a genus of viruses, which include …