2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease: the Task Force on sports cardiology and exercise in patients with …

A Pelliccia, S Sharma, S Gati, M Bäck… - European heart …, 2021 - academic.oup.com
or therapeutic medical strategies. However, the ESC Guidelines do not override in any way
whatsoever the individual responsibility of health professionals to make appropriate and …

Eisenmenger Syndrome: JACC State-of-the-Art Review

A Arvanitaki, MA Gatzoulis, AR Opotowsky… - Journal of the American …, 2022 - jacc.org
Although major breakthroughs in the field of pediatric cardiology, cardiac surgery,
intervention, and overall care improved the outlook of congenital heart disease …

Evaluation of macitentan in patients with Eisenmenger syndrome: results from the randomized, controlled MAESTRO study

MA Gatzoulis, M Landzberg, M Beghetti, RM Berger… - Circulation, 2019 - Am Heart Assoc
Background: Eisenmenger syndrome describes congenital heart disease-associated severe
pulmonary hypertension accompanied by right-to-left shunting. The multicenter, double …

[HTML][HTML] Rare variants in SOX17 are associated with pulmonary arterial hypertension with congenital heart disease

N Zhu, CL Welch, J Wang, PM Allen… - Genome medicine, 2018 - Springer
Background Pulmonary arterial hypertension (PAH) is a rare disease characterized by
distinctive changes in pulmonary arterioles that lead to progressive pulmonary arterial …

Current therapy and outcome of Eisenmenger syndrome: data of the German National Register for congenital heart defects

GP Diller, MA Körten, UMM Bauer, O Miera… - European Heart …, 2016 - academic.oup.com
Aims We aimed to assess the contemporary outcome of Eisenmenger syndrome (ES),
delineate the use of disease targeting therapies (DTT) in these patients and to investigate …

Pathobiology of pulmonary artery hypertension: role of long non-coding RNAs

KR Zahid, U Raza, J Chen, UJ Raj… - Cardiovascular …, 2020 - academic.oup.com
Pulmonary arterial hypertension (PAH) is a disease with complex pathobiology, significant
morbidity and mortality, and remains without a cure. It is characterized by vascular …

Pulmonary hypertension and congenital heart disease: an insight from the REHAP National Registry

R Alonso-Gonzalez, CJ Lopez-Guarch… - International journal of …, 2015 - Elsevier
Background Pulmonary arterial hypertension (PAH) is common in patients with congenital
heart disease (CHD). Although Eisenmenger syndrome may be on decline, other types of …

Pulmonary arterial hypertension associated with congenital heart disease: recent advances and future directions

MA Gatzoulis, M Beghetti, MJ Landzberg… - International journal of …, 2014 - Elsevier
Congenital heart disease (CHD), the most common inborn defect, affects approximately 1%
of all newborns worldwide. Advances in its diagnosis and treatment have led to a dramatic …

68Ga-FAPI PET/CT for molecular assessment of fibroblast activation in right heart in pulmonary arterial hypertension: a single-center, pilot study

Y Gu, K Han, Z Zhang, Z Zhao, C Yan, L Wang… - Journal of Nuclear …, 2023 - Elsevier
Background Positron emission tomography (PET) imaging with radiolabeled fibroblasts
activation protein inhibitor (FAPI) provides the opportunity to directly visualize fibrosis. This …

Echocardiographic Screening for Pulmonary Hypertension in Congenital Heart Disease: JACC Review Topic of the Week

K Dimopoulos, R Condliffe, RMR Tulloh, P Clift… - Journal of the American …, 2018 - jacc.org
Echocardiography is the mainstay in screening for pulmonary hypertension (PH).
International guidelines suggest echocardiographic parameters for suspecting PH, but these …