With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …

In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …

Regenerating periodontal bone tissues in the aggravated inflammatory periodontal
microenvironment under diabetic conditions is a great challenge. Here, a polydopamine …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Immune support by micronutrients is historically based on vitamin C deficiency and
supplementation in scurvy in early times. It has since been established that the complex …

Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Exosomes derived from human adipose-derived stem cells (hADSCs-Exos) have shown
potential as an effective therapeutic tool for repairing bone defects. Although metal-organic …

Biodegradable materials, including natural and synthetic polymers and hydrolyzable metals,
constitute the main components of temporary, implantable medical devices. Besides the …

Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …