Effects of natural products on fructose-induced nonalcoholic fatty liver disease (NAFLD)

Q Chen, T Wang, J Li, S Wang, F Qiu, H Yu, Y Zhang… - Nutrients, 2017 - mdpi.com
As a sugar additive, fructose is widely used in processed foods and beverages. Excessive
fructose consumption can cause hepatic steatosis and dyslipidemia, leading to the …

Oleanolic, ursolic, and betulinic acids as food supplements or pharmaceutical agents for type 2 diabetes: promise or illusion?

FSG Silva, PJ Oliveira, MF Duarte - Journal of agricultural and …, 2016 - ACS Publications
Oleanolic (OA), ursolic (UA), and betulinic (BA) acids are three triterpenic acids (TAs) with
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …

Pentacyclic triterpenes: New tools to fight metabolic syndrome

H Sharma, P Kumar, RR Deshmukh, A Bishayee… - Phytomedicine, 2018 - Elsevier
Background: Metabolic syndrome is a combination of dysregulated cardiometabolic risk
factors characterized by dyslipidemia, impaired glucose tolerance, insulin resistance …

Nutritional and other health properties of olive pomace oil

R Mateos, B Sarria, L Bravo - Critical reviews in food science and …, 2020 - Taylor & Francis
Olive-pomace oil is rich in oleic acid, and thus it can be an interesting dietary fat alternative
as it can allow reaching the recommendation of consuming 20% of total diet energy in the …

High fructose diet-induced metabolic syndrome: pathophysiological mechanism and treatment by traditional Chinese medicine

Y Pan, LD Kong - Pharmacological research, 2018 - Elsevier
Fructose is a natural monosaccharide broadly used in modern society. Over the past few
decades, epidemiological studies have demonstrated that high fructose intake is an …

Baicalein prevents fructose-induced hepatic steatosis in rats: In the regulation of fatty acid de novo synthesis, fatty acid elongation and fatty acid oxidation

P Li, R Zhang, M Wang, Y Chen, Z Chen… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis to non-alcoholic
steatohepatitis (NASH), hepatic fibrosis and even hepatocellular carcinoma, is a liver …

Molecular mechanisms underlying the effects of olive oil triterpenic acids in obesity and related diseases

CM Claro-Cala, F Jiménez-Altayó, S Zagmutt… - Nutrients, 2022 - mdpi.com
Dietary components exert protective effects against obesity and related metabolic and
cardiovascular disturbances by interfering with the molecular pathways leading to these …

Genipin alleviates high‐fat diet‐induced hyperlipidemia and hepatic lipid accumulation in mice via miR‐142a‐5p/SREBP‐1c axis

H Zhong, K Chen, M Feng, W Shao, J Wu… - The FEBS …, 2018 - Wiley Online Library
Hyperlipidemia is a chronic disorder which plays an important role in the development of
cardiovascular diseases, type 2 diabetes, atherosclerosis, hypertension, and nonalcoholic …

Oleanolic acid improves diet-induced obesity by modulating fat preference and inflammation in mice

FZ Djeziri, M Belarbi, B Murtaza, A Hichami… - Biochimie, 2018 - Elsevier
Obesity, triggered by high-fat diet (HFD), is associated to altered gustatory perception of
dietary lipids. Oleanolic acid (OLA), a triterpene, has been reported to exert anti-obesity …

Oleanolic acid modulates the immune-inflammatory response in mice with experimental autoimmune myocarditis and protects from cardiac injury. Therapeutic …

R Martín, C Cordova, JA San Román… - Journal of Molecular and …, 2014 - Elsevier
Myocarditis and dilated cardiomyopathy (DCM) are inflammatory diseases of the
myocardium, for which appropriate treatment remains a major clinical challenge. Oleanolic …