Mechanisms of lncRNA/microRNA interactions in angiogenesis

Z Zhao, W Sun, Z Guo, J Zhang, H Yu, B Liu - Life sciences, 2020 - Elsevier
Angiogenesis is a complex physiological process. However, over the past couple of
decades, abnormally accelerated or pathological angiogenesis has garnered greater …

Insights into biological role of LncRNAs in epithelial-mesenchymal transition

JT Cheng, L Wang, H Wang, FR Tang, WQ Cai, G Sethi… - Cells, 2019 - mdpi.com
Long non-coding RNAs (lncRNAs) are versatile regulators of gene expression and play
crucial roles in diverse biological processes. Epithelial-mesenchymal transition (EMT) is a …

METTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets

KW Hsu, JCY Lai, JS Chang, PH Peng, CH Huang… - Genome biology, 2022 - Springer
Abstract Background DNA N6-methyldeoxyadenosine (6mA) is rarely present in mammalian
cells and its nuclear role remains elusive. Results Here we show that hypoxia induces …

RNA modification: mechanisms and therapeutic targets

L Qiu, Q Jing, Y Li, J Han - Molecular Biomedicine, 2023 - Springer
RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

Propofol facilitates cisplatin sensitivity via lncRNA MALAT1/miR-30e/ATG5 axis through suppressing autophagy in gastric cancer

YF Zhang, CS Li, Y Zhou, XH Lu - Life sciences, 2020 - Elsevier
Aims Recently, chemoresistance has been recognized as an obstacle in the treatment of
gastric cancer (GC). The aim of this study was to investigate the biological functions and …

The expanding roles of long non-coding RNAs in the regulation of cancer stem cells

Z Ma, YY Wang, HW Xin, L Wang, F Arfuso… - The international journal …, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are a novel class of gene regulators playing multifaceted
roles in physiological processes as well as pathological conditions such as cancer. Cancer …

Role of ATP-binding cassette transporters in cancer initiation and progression

S Nobili, A Lapucci, I Landini, M Coronnello… - Seminars in cancer …, 2020 - Elsevier
Abstract ATP Binding Cassette (ABC) transporters, widely studied in cancer for their role in
drug resistance, have been more recently also considered for their contribution to cancer …

Epigenetic modification regulates tumor progression and metastasis through EMT

T Tan, P Shi, MN Abbas, Y Wang… - International …, 2022 - spandidos-publications.com
Epigenetics is the study of heritable molecular determinants that are independent of
phenotypic features. The epigenetic features include DNA methylation, histone …

Long non‑coding RNA MKLN1‑AS aggravates hepatocellular carcinoma progression by functioning as a molecular sponge for miR‑654‑3p, thereby promoting …

W Gao, X Chen, W Chi, M Xue - … journal of molecular …, 2020 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) have recently gained attention due to their important
roles in human cancer types, such as breast and gastric cancer. The present study …

Neuropilins in the context of tumor vasculature

S Niland, JA Eble - International journal of molecular sciences, 2019 - mdpi.com
Neuropilin-1 and Neuropilin-2 form a small family of plasma membrane spanning receptors
originally identified by the binding of semaphorin and vascular endothelial growth factor …