Despite intensive research on peroxisome biochemistry, the role of glutathione in
peroxisomal redox homeostasis has remained a matter of speculation for many years, and …

Glutathione (GSH) is a ubiquitous tripeptide that is biosynthesized in situ at high
concentrations (1–5 mM) and involved in the regulation of cellular homeostasis via multiple …

Multidrug resistance (MDR) is one of the primary factors that produces treatment failure in
patients receiving cancer chemotherapy. MDR is a complex multifactorial phenomenon …

Type 2 diabetes (T2D) is a major worldwide health crisis affecting about 6.2% of the world's
population. Alarmingly, about one in five children in the USA have prediabetes. Glutathione …

Overcoming multidrug resistance (MDR) is one of the major challenges in cancer therapy. In
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …

Iron homeostasisis is integral to normal physiological and biochemical processes of lungs.
The maintenance of iron homeostasis involves the process of intake, storage and output …

This review addresses the urgent need for more targeted and less toxic cancer treatments by
exploring the potential of multi-responsive polymersomes. These advanced nanocarriers are …

Gastric cancer (GC) is a global public health concern that poses a serious threat to human
health owing to its high morbidity and mortality rates. Due to the lack of specificity of …

Chronic obstructive pulmonary disease (COPD), the major leading cause of mortality
worldwide, is a progressive and irreversible respiratory condition characterized by …

Since its discovery in 1958 in the lens of cows, ophthalmic acid (OPH) has stood in the
shadow of its anti‐oxidant analog: glutathione (GSH). Lacking the thiol group that gives GSH …