COVID-19 mechanisms in the human body—What we know so far

A Kumar, RK Narayan, P Prasoon, C Kumari… - Frontiers in …, 2021 - frontiersin.org
More than one and a half years have elapsed since the commencement of the coronavirus
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

Mitochondrial dynamics in SARS-COV2 spike protein treated human microglia: implications for neuro-COVID

E Clough, J Inigo, D Chandra, L Chaves… - Journal of Neuroimmune …, 2021 - Springer
Emerging clinical data from the current COVID-19 pandemic suggests that~ 40% of COVID-
19 patients develop neurological symptoms attributed to viral encephalitis while in COVID …

Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

[PDF][PDF] SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models

B Stolp, M Stern, I Ambiel, K Hofmann, K Morath… - Cell Reports, 2022 - cell.com
SARS-CoV-2 variants of concern (VOCs) display enhanced transmissibility and resistance to
antibody neutralization. Comparing the early 2020 isolate EU-1 to the VOCs Alpha, Beta …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

[HTML][HTML] Mechanisms of action of ozone therapy in emerging viral diseases: Immunomodulatory effects and therapeutic advantages with reference to SARS-CoV-2

A Cenci, I Macchia, V La Sorsa, C Sbarigia… - Frontiers in …, 2022 - frontiersin.org
Medical oxygen-ozone (O 2-O 3) is a successful therapeutic approach accounting on the
assessed beneficial action of ozone in the range 30–45 μg/ml (expanded range 10–80 …

SARS‐CoV‐2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?

J Chen, J Song, L Dai, SR Post… - Journal of medical …, 2022 - Wiley Online Library
The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which
is the causative pathogen for the coronavirus disease 2019 (COVID‐19) pandemic, has …

Inflammasomes and SARS-CoV-2 infection

J Kaivola, TA Nyman, S Matikainen - Viruses, 2021 - mdpi.com
SARS-CoV-2 is a new type of coronavirus that has caused worldwide pandemic. The
disease induced by SARS-CoV-2 is called COVID-19. A majority of people with COVID-19 …