Sirtuin 5-driven meiotic spindle assembly and actin-based migration in mouse oocyte meiosis

C Ma, X Zhang, Y Zhang, H Ruan, X Xu, C Wu, Z Ding… - Heliyon, 2024 - cell.com
Abstract Sirtuin 5 (Sirt5), a member of the Sirtuin family, is involved in various intracellular
biological processes. However, the function of Sirt5 in oocyte maturation has not been …

Maternal genetic variants in kinesin motor domains prematurely increase egg aneuploidy

L Biswas, K Tyc, M Aboelenain, S Sun, I Dundovic… - medRxiv, 2024 - medrxiv.org
The female reproductive lifespan depends on egg quality, particularly euploidy. Mistakes in
meiosis leading to egg aneuploidy are common, but the genetic landscape causing this is …