[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …

Glucose metabolism and oxidative stress in hepatocellular carcinoma: role and possible implications in novel therapeutic strategies

M Mossenta, D Busato, M Dal Bo, G Toffoli - Cancers, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) metabolism is redirected to glycolysis to enhance the
production of metabolic compounds employed by cancer cells to produce proteins, lipids …

Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades

T Efferth, O Kadioglu, MEM Saeed, EJ Seo… - Phytochemistry …, 2021 - Springer
Multidrug resistance is a major factor causing the failure of cancer chemotherapy. Efflux
pumps of the ATP-binding cassette (ABC) transporter family expel a large array of diverse …

[HTML][HTML] Landscape of extracellular vesicles in the tumour microenvironment: Interactions with stromal cells and with non-cell components, and impacts on metabolic …

DX Zhang, LT Vu, NN Ismail, MTN Le… - Seminars in cancer …, 2021 - Elsevier
Extracellular vesicles (EVs) are increasingly recognised as a pivotal player in cell-cell
communication, an attribute of EVs that derives from their ability to transport bioactive …

[HTML][HTML] Network biology and artificial intelligence drive the understanding of the multidrug resistance phenotype in cancer

B Bueschbell, AB Caniceiro, PMS Suzano… - Drug Resistance …, 2022 - Elsevier
Globally with over 10 million deaths per year, cancer is the most transversal disease across
countries, cultures, and ethnicities, affecting both developed and developing regions …

Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancer

S Dogra, SP Elayapillai, D Qu, K Pitts, A Filatenkov… - Cancer Letters, 2023 - Elsevier
Ovarian cancer (OvCa) has a dismal prognosis because of its late-stage diagnosis and the
emergence of chemoresistance. Doublecortin-like kinase 1 (DCLK1) is a serine/threonine …

[HTML][HTML] Recent advances in access to overcome cancer drug resistance by nanocarrier drug delivery system

X Sun, P Zhao, J Lin, K Chen, J Shen - Cancer Drug Resistance, 2023 - ncbi.nlm.nih.gov
Cancer is currently one of the most intractable diseases causing human death. Although the
prognosis of tumor patients has been improved to a certain extent through various modern …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Current advancements in antitumor properties and mechanisms of medicinal components in edible mushrooms

J Xu, R Shen, Z Jiao, W Chen, D Peng, L Wang, N Yu… - Nutrients, 2022 - mdpi.com
Edible and medicinal fungi, a group of eukaryotic organisms with numerous varieties,
including Coriolus versicolor, Ganoderma lucidum, Cordyceps sinensis, Pleurotus ostreatus …

Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line

M Labbozzetta, M Barreca, V Spanò… - Drug Development …, 2022 - Wiley Online Library
Abstract A series of [1, 2] oxazolo [5, 4‐e] isoindole derivatives was evaluated against HL‐60
cell line and its multidrug resistance (MDR) variant, HL‐60R, resistant to doxorubicin and to …