[HTML][HTML] Hesperidin and SARS-CoV-2: New light on the healthy function of citrus fruits

P Bellavite, A Donzelli - Antioxidants, 2020 - mdpi.com
Among the many approaches to Coronavirus disease 2019 (COVID-19) prevention, the
possible role of nutrition has so far been rather underestimated. Foods are very rich in …

[HTML][HTML] Citrus flavonoids as promising phytochemicals targeting diabetes and related complications: A systematic review of in vitro and in vivo studies

GR Gandhi, ABS Vasconcelos, DT Wu, HB Li… - Nutrients, 2020 - mdpi.com
The consumption of plant-based food is important for health promotion, especially
concerning the prevention and management of chronic diseases. Flavonoids are the main …

[HTML][HTML] Antioxidant and Anti-Inflammatory Effects of Citrus Flavonoid Hesperetin: Special Focus on Neurological Disorders

A Khan, M Ikram, JR Hahm, MO Kim - Antioxidants, 2020 - mdpi.com
Neurodegenerative disorders have emerged as a serious health issue in the current era.
The most common neurodegenerative disorders are Alzheimer's disease (AD), Parkinson's …

[HTML][HTML] Beneficial effects of natural flavonoids on neuroinflammation

Y Chen, F Peng, Z Xing, J Chen, C Peng… - Frontiers in …, 2022 - frontiersin.org
Neuroinflammation is the fundamental immune response against multiple factors in the
central nervous system and is characterized by the production of inflammatory mediators …

[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

AC Famurewa, K Renu, MA Eladl… - Biomedicine & …, 2022 - Elsevier
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

[HTML][HTML] Neuroprotective effects and therapeutic potential of the citrus flavonoid hesperetin in neurodegenerative diseases

JA Evans, P Mendonca, KFA Soliman - Nutrients, 2022 - mdpi.com
Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

[HTML][HTML] Bioavailability of hesperidin and its aglycone hesperetin—compounds found in citrus fruits as a parameter conditioning the pro-health potential …

K Wdowiak, J Walkowiak, R Pietrzak, A Bazan-Woźniak… - Nutrients, 2022 - mdpi.com
Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits.
They possess a variety of pharmacological properties such as neuroprotective and …

[HTML][HTML] Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

[HTML][HTML] The neuroprotective effects of targeting key factors of neuronal cell death in neurodegenerative diseases: The role of ER stress, oxidative stress, and …

MS Karvandi, F Sheikhzadeh Hesari… - Frontiers in Cellular …, 2023 - frontiersin.org
Neuronal loss is one of the striking causes of various central nervous system (CNS)
disorders, including major neurodegenerative diseases, such as Alzheimer's disease (AD) …

[HTML][HTML] The benefits of hesperidin in central nervous system disorders, based on the neuroprotective effect

X Li, W Huang, R Tan, C Xu, X Chen, S Li, Y Liu… - Biomedicine & …, 2023 - Elsevier
Disorders of central nervous system (CNS) disorders are considered serious health issues.
The most common CNS diseases include neurodegenerative diseases, mental disorders …