[HTML][HTML] Bridging the gap with multispecific immune cell engagers in cancer and infectious diseases

C Rolin, J Zimmer, C Seguin-Devaux - Cellular & Molecular …, 2024 - nature.com
By binding to multiple antigens simultaneously, multispecific antibodies are expected to
substantially improve both the activity and long-term efficacy of antibody-based …

Activating adaptive immunity by bispecific, T-cell engager antibodies bridging infected and immune-effector cells is a promising novel therapy for chronic hepatitis B

Z Xie, U Protzer - Antiviral Research, 2024 - Elsevier
Bispecific antibodies (bsAbs) are engineered immunoglobulins that combine two different
antigen-binding sites in one molecule. BsAbs can be divided into two molecular formats: IgG …

[HTML][HTML] Antibody drugs targeting SARS-CoV-2: Time for a rethink?

L Liang, B Wang, Q Zhang, S Zhang, S Zhang - Biomedicine & …, 2024 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) heavily burdens human health. Multiple …

Emerging SARS-CoV-2 Variants and Their Impact on Immune Evasion and Vaccine-Induced Immunity

DL Gupta, DN Rao - 2023 - preprints.org
The newly emerged variants of SARS-CoV-2 created a potential threat among societies and
highlighted one of the significant concerns in facing the pandemic. SARS-CoV-2 variants …